Donor cells show promise against Post-Transplant cancer in landmark trial
NCT ID NCT00033475
First seen Jan 17, 2026 · Last updated May 16, 2026 · Updated 15 times
Summary
This study tested a treatment for a rare cancer called post-transplant lymphoproliferative disease (PTLD) that can occur after an organ transplant. The cancer is linked to the Epstein-Barr virus. Researchers gave patients donor white blood cells trained to kill virus-infected cells, along with reducing their usual anti-rejection drugs. The goal was to see if this approach could shrink tumors and improve survival. The trial involved 50 organ transplant recipients.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Birmingham Children's Hospital
Birmingham, England, B4 6NH, United Kingdom
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Central Manchester and Manchester Children's University Hospitals NHS Trust
Manchester, England, M27 4HA, United Kingdom
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Institute of Cancer Research - UK
Sutton, England, SM2 5NG, United Kingdom
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King's College Hospital
London, England, SE5 8RX, United Kingdom
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Northern General Hospital
Sheffield, England, S5 7AU, United Kingdom
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Papworth Hospital
Cambridge, England, CB3 8RE, United Kingdom
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Royal Free and University College Medical School
London, England, NW3 2PF, United Kingdom
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Royal Infirmary - Castle
Glasgow, Scotland, G4 0SF, United Kingdom
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Royal Infirmary of Edinburgh at Little France
Edinburgh, Scotland, EH16 4SA, United Kingdom
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University of Edinburgh
Edinburgh, Scotland, EH8 1QH, United Kingdom
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University of Edinburgh Laboratory for Clinical and Molecular Virology
Edinburgh, Scotland, EH9 1QH, United Kingdom
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Wythenshawe Hospital
Manchester, England, M23 9LJ, United Kingdom
Conditions
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