New pill could help vapers kick the habit for good

NCT ID NCT07392125

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests whether cytisinicline, a plant-based tablet, can help adults quit nicotine vaping. 800 daily e-cigarette users will receive either the drug or a placebo for 12 weeks, plus behavioral support. The goal is to see if more people can stop vaping completely during the final month of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cytisinicline (also called cytisine) - a plant-based tablet to reduce nicotine cravings

What this could lead to

If successful, this could provide a new, non-nicotine medication to help people quit vaping, potentially reducing nicotine addiction.

What could go wrong

This is an early Phase 3 trial, so results are not yet known. The drug may not work better than placebo, and side effects are possible. Success depends on long-term abstinence.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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