Music and lidocaine timing: a simple recipe for a gentler cystoscopy?
NCT ID NCT07795255
First seen Aug 31, 2026 · Last updated Sep 02, 2026 · Updated 2 times
Summary
This trial tests whether listening to music or letting numbing medication sit longer can reduce pain during cystoscopy, a procedure that examines the bladder. About 1,740 people undergoing cystoscopy for bladder cancer diagnosis or surveillance will be randomly assigned to different combinations of music and lidocaine dwell times. Researchers will measure pain and anxiety levels to see which approach works best.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Listening to music via headphones and lidocaine numbing medication with different dwell times
- What this could lead to
- If it works, this could give doctors simple, low-cost ways to make cystoscopy more comfortable for patients, reducing pain and anxiety during the procedure.
- What could go wrong
- The trial is testing two interventions at once, so it may be hard to tell which one helps. Also, results may vary depending on individual pain tolerance and music preference.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 1,740 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2031
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a US federal agency other than the NIH.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Undergoing office-based cystoscopy for bladder cancer diagnosis, surveillance, or evaluation of anatomic abnormalities. Exclusion Criteria: * Allergy to or intolerance of lidocaine. * Intolerance of all offered music genre playlists (Jazz, Classical, New Age), such that no acceptable music option exists. * Known pregnancy or lactation (routine pregnancy testing is not required)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
5 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Novant Health New Hanover Regional Medical Center
Wilmington, North Carolina, 28401, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
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University of North Carolina
Chapel Hill, North Carolina, 27599, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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White River Junction Veterans Healthcare System
White River Junction, Vermont, 05009, United States
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Other studies related to the condition(s) this trial covers.
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- A simple urine test could revolutionize bladder cancer detection
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- Could bladder bacteria trigger cancer? new study investigates
- Bladder cancer surgery: new clues in fluid and DNA may predict recurrence