Cystinuria drug trial pulled before it even started
NCT ID NCT04147871
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study was designed to test whether ADV7103, a combination of potassium citrate and potassium bicarbonate, could help people with cystinuria by making their urine less acidic. The goal was to see if it could raise urine pH to 7.0 or higher, which might reduce kidney stone formation. However, the trial was withdrawn before enrolling any participants, so no data were collected.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ADV7103 (a mix of potassium citrate and potassium bicarbonate)
What this could lead to
If it had worked, this could have pointed toward a better way to manage cystinuria by controlling urine acidity to prevent kidney stones.
What could go wrong
The trial was withdrawn before enrolling anyone, so no results are available. Even if run, it was an early-stage study with a short 7-day treatment period, so long-term benefits and safety would remain uncertain.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
Contacts and locations
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Locations
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CHRU Lille
Lille, Lille, 59000, France
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CHU Grenoble
Grenoble, Grenoble Cedex, 38043, France
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CHU Pitié-Salpétrière
Paris, Paris, 15013, France
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CHU Purpan
Toulouse, Toulouse Cedex 9, 31059, France
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CHU Reims
Reims, Reims, 51100, France
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Centre Hospitalier Universitaire de Lyon - Hôpital Femme Mère Enfant
Bron, 69500, France
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Cliniques Universitaires Saint-Luc
Brussels, Brussels Capital, Belgium
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Hôpital Américain CHU de Reims
Reims, Reims, 51092, France
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Hôpital Necker AP-HP
Paris, Paris, 75015, France
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Hôpital Necker Enfants Malades
Paris, Paris, 75015, France
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Hôpital Ténon - Explorations fonctionnelles Mutlidisciplinaires et INSERM UMR S 1155
Paris, Paris, 75020, France
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UZ Leuven, Gasthuisberg Hospital
Leuven, Leuven, Belgium