Could a diabetes drug boost psoriasis treatment?

NCT ID NCT07375654

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding metformin, a common diabetes drug, to cyclosporine works better for psoriasis than cyclosporine alone. Thirty-two adults with moderate to severe psoriasis took part. Researchers measured skin improvement, body surface area affected, and quality of life over three months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cyclosporine and metformin

What this could lead to

If adding metformin works better, it could offer a more effective way to control psoriasis with the same drugs already available.

What could go wrong

This is a very small, early-phase trial with only 32 people. Results may not apply to everyone, and the combination could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cairo University

    Cairo, Cairo Governorate, Egypt 02002, Egypt