New study tests which braces wire hurts less and works better

NCT ID NCT06653881

First seen Feb 13, 2026 · Last updated Jun 23, 2026 · Updated 17 times

Summary

This study compared two types of archwires used in braces: conventional nickel-titanium and copper-nickel-titanium. The goal was to see which wire straightens teeth more efficiently and causes less pain, measured using a pain scale and a biomarker called prostaglandin E2. Thirty people aged 18 to 25 with moderate crowding took part. The results may help orthodontists choose the best wire for a more comfortable treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • PGIDS

    Rohtak, Haryana, 124001, India

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

archwires (conventional nickel-titanium and copper-nickel-titanium)

What this could lead to

If successful, this could help orthodontists choose which archwire causes less pain and aligns teeth faster, improving patient comfort.

What could go wrong

This is a small, completed study with only 30 participants. Results may not apply to all patients or types of crowding.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.