Gene-Edited cells take aim at stubborn autoimmune diseases

NCT ID NCT07549698

First seen May 02, 2026 · Last updated May 24, 2026 · Updated 3 times

Summary

This early-stage trial is testing a new treatment called CTX112 for adults with two serious autoimmune blood disorders: immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA). These conditions cause the immune system to attack the body's own blood cells. CTX112 uses CRISPR gene editing to create donor T cells that target and destroy the faulty immune cells causing the disease. The study aims to see if this approach is safe and can help control the disease, though ongoing management may still be needed.

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