Experimental drug ANX005 targets blood cell destruction in autoimmune anemia

NCT ID NCT04691570

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This phase 2 trial investigates ANX005, an investigational drug given intravenously, for people with warm autoimmune hemolytic anemia (wAIHA). The study aims to assess the safety and tolerability of repeated doses, and to measure changes in blood markers like hemoglobin and bilirubin. Participants are adults with confirmed wAIHA and low hemoglobin levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ANX005
What this could lead to
If successful, ANX005 could offer a new treatment option for people with warm autoimmune hemolytic anemia, potentially improving red blood cell counts and reducing disease symptoms.
What could go wrong
This is a small, early-phase trial with only 7 participants, so results may not apply broadly. The drug may cause side effects or fail to show meaningful benefit.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site 01

    Rochester, Minnesota, 55905, United States

  • Investigational Site 02

    Sofia, Bulgaria

  • Investigational Site 03

    Melbourne, Australia

  • Investigational Site 04

    Vienna, Austria

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