New combo therapy aims to ease strain on heart in rare lung condition

NCT ID NCT05140525

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining two medications (Riociguat and Macitentan) with a balloon procedure to open blocked lung arteries can improve heart function in people with chronic thromboembolic pulmonary hypertension (CTEPH). The trial enrolls 15 adults who cannot have surgery or still have symptoms after surgery. The goal is to see if this approach helps the right side of the heart pump more efficiently.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CTEPH are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.