New combo therapy aims to ease strain on heart in rare lung condition
NCT ID NCT05140525
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining two medications (Riociguat and Macitentan) with a balloon procedure to open blocked lung arteries can improve heart function in people with chronic thromboembolic pulmonary hypertension (CTEPH). The trial enrolls 15 adults who cannot have surgery or still have symptoms after surgery. The goal is to see if this approach helps the right side of the heart pump more efficiently.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
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Other studies related to the condition(s) this trial covers.