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Blood test may predict lung cancer outcomes before surgery

NCT ID NCT05382052

Ongoing Knowledge-focused Sponsor: Fundación GECP Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking at 100 people with stage IIIA lung cancer who are getting treatment before surgery. Researchers want to see if a blood test that looks for tumor DNA (ctDNA) can predict how well patients do. If the tumor DNA disappears after treatment, it might mean a better chance of staying cancer-free.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could show that a simple blood test (ctDNA) helps doctors predict which lung cancer patients will do well after pre-surgery treatment, guiding better care.
What could go wrong
This is an observational study, not a treatment trial. It only looks for patterns, so it won't directly change care. Results may not apply to all patients or be conclusive.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEOADJUVANT TREATMENT NON-SMALL CELL LUNG CANCER STAGE III

Contacts and locations

Locations

  • Complejo Hospitalario de Navarra

    Pamplona, Iruña, 31008, Spain

  • Hospital Clínico San Carlos

    Madrid, Madrid, 28040, Spain

  • Hospital Clínico Universitario de Valladolid

    Valladolid, Valladolid, 47003, Spain

  • Hospital Clínico de Valencia

    Valencia, Valencia, 46010, Spain

  • Hospital De Basurto

    Bilbao, Bilbao, 48013, Spain

  • Hospital General Universitario de Alicante

    Alicante, Alicante, 03010, Spain

  • Hospital Germans Trias I Pujol

    Badalona, Barcelona, 08916, Spain

  • Hospital Universitari Quiron Dexeus

    Barcelona, Barcelona, 08028, Spain

  • Hospital Universitari Son Llatzer

    Palma de Mallorca, Palma de Mallorca, 07198, Spain

  • Hospital Universitari Vall d' Hebron

    Barcelona, Barcelona, 08035, Spain

  • Hospital Universitario De A Coruna

    A Coruña, A Coruña, 15006, Spain

  • Hospital Universitario Fundación Jiménez Díaz

    Madrid, Madrid, 28040, Spain

  • Hospital Universitario La Fe

    Valencia, Valencia, 46026, Spain

  • Hospital Universitario Lucus Augusti

    Lugo, Lugo, 27003, Spain

  • Hospital Universitario Puerta de Hierro

    Majadahonda, Madrid, 28222, Spain

  • Hospital Universitario Regional de Málaga

    Málaga, Málaga, 29010, Spain

  • Hospital Universitario Reina Sofia

    Córdoba, Córdoba, 14004, Spain

  • Hospital Universitario de Jaén

    Jaén, Jaén, 23007, Spain

  • Hospital Universitario la Paz

    Madrid, Madrid, 28046, Spain

  • ICO Girona, Hospital Josep Trueta

    Girona, Girona, 17007, Spain

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