Blood test may replace biopsies for rare lymphoma monitoring

NCT ID NCT06089941

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether analyzing tumor DNA from blood samples (called ctDNA) can be a reliable way to monitor peripheral T-cell lymphoma, a rare blood cancer. Researchers will take blood from 45 patients at diagnosis, during treatment, and at relapse to see if the method works. The goal is to find out if this non-invasive approach can track the cancer as well as standard tissue biopsies.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test to track lymphoma and guide treatment decisions without repeated tissue biopsies.
What could go wrong
This is a small, early feasibility study (45 people) that only checks if the method works. It does not test a treatment, so even if successful, it may not directly improve outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Henri Becquerel

    Rouen, France

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Other studies related to the condition(s) this trial covers.