Blood test may predict cancer recurrence in head and neck patients

NCT ID NCT06479070

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether measuring circulating tumor DNA (ctDNA) in the blood can predict if cancer will come back after radiation therapy. Researchers will collect blood samples from 188 patients with advanced head and neck cancer before, during, and after treatment. The goal is to see if a drop in ctDNA levels one month after treatment can forecast progression-free survival at two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test to predict cancer recurrence earlier, helping doctors tailor follow-up care.

What could go wrong

This is an observational study, not a treatment trial. It may not show a clear link between ctDNA levels and outcomes, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Head and Neck Neoplasms head and neck squamous cell carcinoma neoplasm squamous cell carcinoma upper aerodigestive tract neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • CHU Besançon

    RECRUITING

    Besançon, 25030, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre François Baclesse

    RECRUITING

    Caen, Caen, 14076, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Georges-François Leclerc

    RECRUITING

    Dijon, 21000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut de Cancérologie Strasbourg Europe

    RECRUITING

    Strasbourg, 67033, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de Cancérologie de Lorraine

    RECRUITING

    Vandœuvre-lès-Nancy, Grand Est, 54500, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Intitut Jean Godinot

    RECRUITING

    Reims, 51100, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Zurich (USZ)

    RECRUITING

    Zurich, Canton of Zurich, 8091, Switzerland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••