Why do healthy people get this fungal infection? new study aims to find out

NCT ID NCT00001352

Recruiting now Knowledge-focused Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 5 times

Summary

This study looks at 800 healthy adults who have cryptococcosis, a fungal infection that usually only harms people with weak immune systems. Researchers want to learn why these otherwise healthy people get sick, how their immune system responds, and how the disease progresses over time. No new treatments are being tested; the goal is to gather knowledge.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could reveal why some healthy people get cryptococcosis and point to better ways to predict or treat it.
What could go wrong: This is an observational study, not a treatment trial. It may not lead to any new therapies, and results may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cryptococcal meningitis cryptococcosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRYPTOCOCCAL INFECTION CRYPTOCOCCAL MENINGITIS CRYPTOCOCCAL PNEUMONIA CRYPTOCOCCOSIS PULMONARY CRYPTOCOCCOSIS

Contacts and locations

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

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