Freeze your cough away? new trial tests cryotherapy for chronic hackers
NCT ID NCT05665244
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a procedure called laryngeal cryotherapy, which freezes overactive nerves in the throat to reduce chronic cough. Researchers will enroll 28 adults with neurogenic cough (a cough lasting 8+ weeks with no other cause). Participants will receive one cryotherapy treatment and be followed for 6 months to see if their cough symptoms and quality of life improve.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- laryngeal cryotherapy (freezing throat tissue)
- What this could lead to
- If it works, this could offer a new, non-drug option for people with hard-to-treat chronic cough.
- What could go wrong
- This is a very small pilot study (28 people) with no comparison group, so results may not be reliable or apply to everyone. Freezing throat tissue carries risks like temporary hoarseness or swallowing problems.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75235, United States
Contact Email: •••••@•••••