Frozen platelets may be just as good as fresh for heart surgery bleeding

NCT ID NCT04709705

First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 23 times

Summary

This study tested whether frozen platelets can control bleeding as well as standard fresh platelets in 161 adults undergoing heart surgery with a heart-lung machine. The goal was to see if the frozen version is a safe and effective alternative. Results will help determine if frozen platelets can be used more widely to manage blood loss during these procedures.

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Contacts and locations

Locations

  • Abington Memorial Hospital

    Abington, Pennsylvania, 19001, United States

  • Dartmouth Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

  • Duke University Hospital

    Durham, North Carolina, 27710, United States

  • George Washington University

    Washington D.C., District of Columbia, 20037, United States

  • Inova Cardiac Vascular

    Falls Church, Virginia, 22042, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21218, United States

  • Maine Medical Center

    Portland, Maine, 04102, United States

  • OU Medical Center

    Oklahoma City, Oklahoma, 73104, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • The Ohio State Univ. Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • Thomas Jefferson Univ. Hospital

    Philadelphia, Pennsylvania, 19107, United States

  • UF Health

    Gainesville, Florida, 32608, United States

  • University of Alabama

    Birmingham, Alabama, 35205, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Maryland Medical Center

    Baltimore, Maryland, 21201, United States

  • University of Virginia Medical Center

    Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.