New hope for kids with Tough-to-Treat Crohn's disease

NCT ID NCT04779320

Summary

This study is testing a medication called vedolizumab to see if it can help children and teenagers with moderate to severe Crohn's disease who haven't gotten better with other standard treatments. About 120 participants will receive the drug through an IV to try to reduce gut inflammation and achieve remission. The main goal is to see if the treatment keeps the disease under control for a year, allowing kids to feel better and grow normally.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CROHN'S DISEASE (CD) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AOU dell'Universita degli Studi della Campania Luigi Vanvitelli

    NOT_YET_RECRUITING

    Naples, Campania, 80131, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ASST di Monza - Azienda Ospedaliera San Gerardo

    NOT_YET_RECRUITING

    Monza, Lombardy, 20900, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Advocate Children's Hospital Park Ridge

    RECRUITING

    Park Ridge, Illinois, 60068, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Attikon University General Hospital

    RECRUITING

    Athens, Attica, 124 62, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda Ospedaliera Universitaria Federico II

    NOT_YET_RECRUITING

    Naples, Campania, 80131, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Azienda USL di Bologna

    NOT_YET_RECRUITING

    Bologna, Emilia-Romagna, 40133, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Barts Health NHS Trust

    NOT_YET_RECRUITING

    London, E1 1BB, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing Children Hospital,Capital Medical University

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100045, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Birmingham Children's Hospital NHS Foundation Trust

    NOT_YET_RECRUITING

    Birmingham, West Midlands, B4 6NH, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Borsod-Abauj-Zemplen Megyei Kozponti Korhaz es Egyetemi Oktato Korhaz

    RECRUITING

    Miskolc, Borsod-Abauj Zemplen county, 3526, Hungary

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Boston Children's Hospital

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • British Columbia Children's Hospital

    NOT_YET_RECRUITING

    Vancouver, British Columbia, V6H3V4, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Carilion Children's Tanglewood Center

    RECRUITING

    Roanoke, Virginia, 24018, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Carmel Medical Center

    NOT_YET_RECRUITING

    Haifa, 34362, Israel

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cedars Sinai Medical Center

    WITHDRAWN

    Los Angeles, California, 90048, United States

  • Centre Hospitalier Universitaire Sainte-Justine

    NOT_YET_RECRUITING

    Montreal, Quebec, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital "Agia Sofia"

    RECRUITING

    Athens, Greece

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital at Westmead

    NOT_YET_RECRUITING

    Westmead, New South Wales, 2145, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital of Fudan University

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 201102, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Children's Hospital of Pittsburgh

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Childrens Center For Digestive Healthcare

    RECRUITING

    Atlanta, Georgia, 30342, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Copernicus Podmiot Leczniczy Sp. z o.o.

    NOT_YET_RECRUITING

    Gdansk, Pomeranian Voivodeship, 80-803, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Detska fakultna nemocnica s poliklinikou Banska Bystrica

    TERMINATED

    Banská Bystrica, 974 09, Slovakia

  • Fakultni Thomayerova Nemocnice

    NOT_YET_RECRUITING

    Prague, Praha, Hlavni Mesto, 140 00, Czechia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fakultni nemocnice Kralovske Vinohrady

    NOT_YET_RECRUITING

    Prague, Praha, Hlavni Mesto, 100 34, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Fakultni nemocnice Ostrava

    NOT_YET_RECRUITING

    Ostrava, Czechia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gachon University Gil Medical Center

    RECRUITING

    Incheon, Incheon Gwang'yeogsi, 21565, South Korea

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gornoslaskie Centrum Zdrowia Dziecka Im. Sw. Jana Pawla II Spsk Nr 6 Sum W Katowicach

    NOT_YET_RECRUITING

    Katowice, Silesian Voivodeship, 40-752, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Goryeb Children's Hospital

    RECRUITING

    Morristown, New Jersey, 07960, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Great Ormond Street Hospital (GOSH)

    NOT_YET_RECRUITING

    London, London, City of, WC1N 3AJ, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hadassah Medical Center - PPDS

    NOT_YET_RECRUITING

    Jerusalem, 91120, Israel

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hasbro Children's Hospital

    WITHDRAWN

    Providence, Rhode Island, 02903, United States

  • Henan Children's Hospital(Zhengzhou Children's Hospital)

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Infantil Universitario Nino Jesus - PIN

    WITHDRAWN

    Madrid, 28009, Spain

  • Hospital Regional Universitario de Malaga - Hospital Materno Infantil

    WITHDRAWN

    Málaga, 29011, Spain

  • Hospital Sant Joan de Deu - PIN

    WITHDRAWN

    Esplugues de Llobregat, Barcelona, 8950, Spain

  • Hospital Universitario Virgen del Rocio - PPDS

    WITHDRAWN

    Seville, 41013, Spain

  • Hospital de Sagunto

    WITHDRAWN

    Sagunto, Valencia, 46520, Spain

  • Hospital of Lithuanian University of Health Sciences Kaunas Clinics

    WITHDRAWN

    Kaunas, Kaunas County, LT-50161, Lithuania

  • I.H.S Health LLC

    WITHDRAWN

    Kissimmee, Florida, 34741, United States

  • Instytut Centrum Zdrowia Matki Polki

    NOT_YET_RECRUITING

    Lodz, Łódź Voivodeship, 93-338, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instytut Pomnik Centrum Zdrowia Dziecka

    RECRUITING

    Warsaw, Masovian Voivodeship, 04-736, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ippokratio General Hospital of Thessaloniki

    NOT_YET_RECRUITING

    Thessaloniki, 564 29, Greece

  • Ippokratio General Hospital of Thessaloniki

    RECRUITING

    Thessaloniki, 564 29, Greece

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Japanese Red Cross Kumamoto Hospital

    RECRUITING

    Kumamoto, Kumamoto, 861-8520, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Johns Hopkins University

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Juntendo University Hospital

    RECRUITING

    Bunkyo-Ku, Tokyo, 113-8431, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Kings College Hospital

    NOT_YET_RECRUITING

    London, London, City of, SE5 9RS, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Klinika Za Djecje Bolesti Zagreb

    RECRUITING

    Zagreb, City of Zagreb, 10000, Croatia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Korczowski Bartosz, Gabinet Lekarski

    RECRUITING

    Rzeszów, Podkarpackie Voivodeship, 35-302, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kurume University Hospital

    RECRUITING

    Kurume-Shi, Hukuoka, 830-0011, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Kyungpook National University Chilgok hospital

    RECRUITING

    Daegu, Daegu Gwang'yeogsi, 41404, South Korea

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • London Health Sciences Centre

    NOT_YET_RECRUITING

    London, Ontario, N6A 4G5, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MNGI Digestive Health, PA

    RECRUITING

    Minneapolis, Minnesota, 55413, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic - PIN

    NOT_YET_RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Monash Health, Monash Medical Centre

    NOT_YET_RECRUITING

    Clayton, Victoria, 3168, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Narodny ustav detskych chorob

    TERMINATED

    Bratislava, 833 40, Slovakia

  • National Center for Child Health and Development

    RECRUITING

    Setagaya-Ku, Tokyo, 157-8535, Japan

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Noahs Ark Childrens Hospital for Wales - PPDS - PIN

    NOT_YET_RECRUITING

    Cardiff, South Glamorgan, CF14 4XW, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Phoenix Childrens Hospital

    NOT_YET_RECRUITING

    Phoenix, Arizona, 85016, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Queensland Childrens Hospital

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rady Childrens Hospital San Diego - PIN

    NOT_YET_RECRUITING

    San Diego, California, 92123, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rambam Medical Center - PPDS

    NOT_YET_RECRUITING

    Haifa, 31096, Israel

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Riley Hospital For Children

    WITHDRAWN

    Indianapolis, Indiana, 46202, United States

  • Royal Children's Hospital Melbourne - PIN

    NOT_YET_RECRUITING

    Parkville, Victoria, 3052, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Manchester Children's Hospital - PPDS

    NOT_YET_RECRUITING

    Manchester, M27 4HA, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • SPZOZ Centralny Szpital Kliniczny UM w Lodzi

    NOT_YET_RECRUITING

    Lodz, 91-738, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • SUNY Upstate Medical Center

    WITHDRAWN

    Syracuse, New York, 13202, United States

  • Samsung Medical Center - PPDS

    RECRUITING

    Seoul, 6351, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sapienza University of Rome

    RECRUITING

    Rome, Lazio, 161, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Schneider Childrens Medical Center of Israel Petah Tikvah PIN

    NOT_YET_RECRUITING

    Petah Tikva, Central District, 49202, Israel

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Semmelweis Egyetem

    NOT_YET_RECRUITING

    Budapest, 1083, Hungary

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seoul National University Hospital

    RECRUITING

    Seongnam, Seoul, South Korea

    Contact

    Contact Email: •••••@•••••

  • Shaare Zedek Medical Center

    NOT_YET_RECRUITING

    Jerusalem, 91031, Israel

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Soroka University Medical Centre

    NOT_YET_RECRUITING

    Beersheba, 84101, Israel

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stony Brook University Medical Center

    RECRUITING

    Stony Brook, New York, 11794, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont

    RECRUITING

    Szeged, Csongrád megye, 6720, Hungary

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tel Aviv Sourasky Medical Center PPDS

    NOT_YET_RECRUITING

    Jerusalem, Jerusalem, 90000, Israel

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Children's Hospital Zhejiang UniversitySchool of Medicine

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, 310003, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Steven and Alexandra Cohen Childrens Medical Center of New York - BRANY - PPDS

    RECRUITING

    New Hyde Park, New York, 11042, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Twoja Przychodnia SCM

    RECRUITING

    Szczecin, West Pomeranian Voivodeship, 71-434, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UZ Antwerpen

    NOT_YET_RECRUITING

    Edegem, Antwerpen, 2650, Belgium

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UZ Leuven

    NOT_YET_RECRUITING

    Leuven, Vlaams Brabant, 3000, Belgium

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universita degli Studi di Padova

    NOT_YET_RECRUITING

    Padua, Veneto, 35122, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitair Ziekenhuis Brussel - PIN

    NOT_YET_RECRUITING

    Jette, Brussels Capital, 1090, Belgium

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Center Zagreb

    RECRUITING

    Zagreb, City of Zagreb, 10000, Croatia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Centre Split

    RECRUITING

    Split, 21000, Croatia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospitals Cleveland Medical Center

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Alberta Hospital

    NOT_YET_RECRUITING

    Edmonton, Alberta, AB T6G 2B7, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California San Francisco

    WITHDRAWN

    San Francisco, California, 94143, United States

  • University of Rochester Medical Center PPDS

    WITHDRAWN

    Rochester, New York, 14642, United States

  • Uniwersytecki Szpital Dzieciecy

    NOT_YET_RECRUITING

    Krakow, Lesser Poland Voivodeship, 30-663, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Uniwersytecki Szpital Kliniczny im. Jana Mikulicza Radeckiego we Wroclawiu

    NOT_YET_RECRUITING

    Wroclaw, Lower Silesian Voivodeship, 50-369, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vilnius University Hospital Santaros Klinikos

    WITHDRAWN

    Vilnius, Vilnius County, 8406, Lithuania

  • WIP Warsaw IBD Point Profesor Kierkus

    NOT_YET_RECRUITING

    Warsaw, Masovian Voivodeship, 00-728, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.