New combo therapy aims to boost Crohn's treatment
NCT ID NCT07483099
First seen Mar 21, 2026 · Last updated May 24, 2026 · Updated 7 times
Summary
This study tests whether adding an experimental drug (LY4395089) to the existing treatment mirikizumab works better than mirikizumab alone for adults with moderate-to-severe Crohn's disease. About 60 participants will be followed for 62 weeks to see if the combination improves bowel healing and reduces symptoms. The goal is to find a more effective way to control this chronic condition.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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AZ Delta vzw
NOT_YET_RECRUITINGRoeselare, 8800, Belgium
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AZ Maria Middelares
NOT_YET_RECRUITINGGhent, 9000, Belgium
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Affiliated Hospital of Jiangsu University
NOT_YET_RECRUITINGZhenjiang, 212000, China
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Assuta Ashdod Medical Center
NOT_YET_RECRUITINGAshdod, 7747629, Israel
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Atlanta Gastroenterology Associates - Peachtree Dunwoody
RECRUITINGAtlanta, Georgia, 30342, United States
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Azienda Ospedaliera Universitaria Careggi
NOT_YET_RECRUITINGFlorence, 50134, Italy
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BR Trials - Ensaios Clinicos e Consultoria
NOT_YET_RECRUITINGSão Paulo, 01236030, Brazil
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Biopharma Informatic, LLC
NOT_YET_RECRUITINGLos Angeles, California, 90035, United States
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CEDOES
NOT_YET_RECRUITINGVitória, 29055450, Brazil
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CPCLIN
NOT_YET_RECRUITINGSão Paulo, 01228-200, Brazil
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CPHosp Medicina, Ensino e Pesquisa (CPQuali)
NOT_YET_RECRUITINGSão Paulo, 01228-000, Brazil
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Centro Digestivo de Curitiba
NOT_YET_RECRUITINGCuritiba, 80430-180, Brazil
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Centro de Pesquisa Clínica de Marília - CPCLIM
NOT_YET_RECRUITINGMarília, 17504-072, Brazil
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Changzhou Second People's Hospital
NOT_YET_RECRUITINGChangzhou, 213000, China
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Charité Universitaetsmedizin Berlin - Campus Mitte
NOT_YET_RECRUITINGBerlin, 10117, Germany
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Clínica Hepatogastro JK
NOT_YET_RECRUITINGSão Paulo, 04077-020, Brazil
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Cotton O'Neil Digestive Health Center
RECRUITINGTopeka, Kansas, 66606, United States
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ETG Siedlce
NOT_YET_RECRUITINGSiedlce, 08-110, Poland
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ETG Zamość
NOT_YET_RECRUITINGZamość, 22-400, Poland
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Ezy Medical Research
RECRUITINGMiami Lakes, Florida, 33015, United States
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Fondazione IRCCS San Gerardo dei Tintori
NOT_YET_RECRUITINGMonza, 20900, Italy
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Fondazione Policlinico Universitario Agostino Gemelli
NOT_YET_RECRUITINGRoma, 00168, Italy
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Fundação Universidade de Caxias do Sul (FUCS)
NOT_YET_RECRUITINGCaxias do Sul, 95070-560, Brazil
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Gastro Health Research - Miami
NOT_YET_RECRUITINGMiami, Florida, 33176, United States
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Gastroenterology Associates of Western Michigan, PLC d.b.a. West Michigan Clinical Research Center
NOT_YET_RECRUITINGWyoming, Michigan, 49519, United States
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Geomedical Egészségügyi Központ
NOT_YET_RECRUITINGBudapest, 1066, Hungary
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Gyncentrum sp. z o.o. NZOZ Holsamed - oddział Libero
NOT_YET_RECRUITINGKatowice, 40-600, Poland
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Hadassah Medical Center
NOT_YET_RECRUITINGJerusalem, 9112001, Israel
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Huizhou Central People's Hospital
NOT_YET_RECRUITINGHuizhou, 516001, China
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Humanitas
NOT_YET_RECRUITINGRozzano, 20089, Italy
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Innovo Research - Wilmington Gastroenterology Associates
NOT_YET_RECRUITINGWilmington, North Carolina, 28403, United States
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KAD Clinical Research
NOT_YET_RECRUITINGSt Louis, Missouri, 63123, United States
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Komarom-Esztergom Varmegyei Szent Borbala Korhaz
NOT_YET_RECRUITINGTatabánya, 2800, Hungary
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Loema Instituto de Pesquisa Clinica
NOT_YET_RECRUITINGCampinas, 13092-133, Brazil
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London Digestive Disease Institute
NOT_YET_RECRUITINGLondon, N6K 1M6, Canada
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Mayo Clinic in Arizona - Scottsdale
NOT_YET_RECRUITINGScottsdale, Arizona, 85259, United States
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Medical Network Spółka z o.o. WIP Warsaw IBD Point Profesor Kierkuś
NOT_YET_RECRUITINGWarsaw, 04-501, Poland
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Medrise Sp. z o.o.
NOT_YET_RECRUITINGLublin, 20-582, Poland
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Om Research LLC
NOT_YET_RECRUITINGOxnard, California, 93030, United States
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One of a Kind Clinical Research Center - Kingwood
NOT_YET_RECRUITINGKingwood, Texas, 77339, United States
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Oslomed Centrum Medyczne
NOT_YET_RECRUITINGKrakow, 31-228, Poland
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Ospedale Sacro Cuore Don G. Calabria
NOT_YET_RECRUITINGNegrar, 37024, Italy
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Ospedale San Raffaele
NOT_YET_RECRUITINGMilan, 20132, Italy
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Prairie Institute of Liver and Luminal Advanced Research Ltd (PILLAR)
NOT_YET_RECRUITINGLethbridge, T1J 4G9, Canada
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Rabin Medical Center
NOT_YET_RECRUITINGPetah Tikva, 4941492, Israel
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Rambam Health Care Campus
NOT_YET_RECRUITINGHaifa, 3109601, Israel
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Rush University Medical Center
NOT_YET_RECRUITINGChicago, Illinois, 60612, United States
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Semmelweis Egyetem
NOT_YET_RECRUITINGBudapest, 1082, Hungary
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Shaare Zedek Medical Center
NOT_YET_RECRUITINGJerusalem, 9103102, Israel
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Sheba Medical Center
NOT_YET_RECRUITINGRamat Gan, 5262100, Israel
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Solare Trials
NOT_YET_RECRUITINGSão Paulo, 01307-002, Brazil
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Sonomed Sp. z o. o.
NOT_YET_RECRUITINGSzczecin, 71-685, Poland
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South Denver Gastroenterology
NOT_YET_RECRUITINGEnglewood, Colorado, 80113, United States
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Southern Star Research Institute
RECRUITINGSan Antonio, Texas, 78229, United States
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St. Marien- und St. Annastiftskrankenhaus
NOT_YET_RECRUITINGLudwigshafen, 67067, Germany
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Studiengesellschaft BSF Unternehmergesellschaft
NOT_YET_RECRUITINGHalle, 06108, Germany
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Studienzentrum MVZ Dachau
NOT_YET_RECRUITINGDachau, 85221, Germany
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Tdda Inc.
NOT_YET_RECRUITINGVaughan, L4L 4Y7, Canada
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The First Affiliated Hospital, Sun Yat-sen University
NOT_YET_RECRUITINGGuangzhou, 510080, China
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The Second Affiliated Hospital YuYing Childens Hospital of Wenzhou Medical university
NOT_YET_RECRUITINGWenzhou, 325000, China
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The Second Affiliated Hospital of Soochow University
NOT_YET_RECRUITINGSuzhou, 215004, China
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The Second Affiliated hospital of Zhejiang University school of medicine
NOT_YET_RECRUITINGHangzhou, 310052, China
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The Second Xiangya Hospital of Central South University
NOT_YET_RECRUITINGChangsha, 410011, China
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Twoja Przychodnia PCM
NOT_YET_RECRUITINGPoznan, 60-324, Poland
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Twoja Przychodnia SCM
NOT_YET_RECRUITINGSzczecin, 71-434, Poland
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UZ Gent
NOT_YET_RECRUITINGGhent, 9000, Belgium
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UZ Leuven
NOT_YET_RECRUITINGLeuven, 3000, Belgium
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Universitaetsklinikum Ulm
NOT_YET_RECRUITINGUlm, 89081, Germany
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Vector Clinical Trials
RECRUITINGLas Vegas, Nevada, 89128, United States
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WSD MEDI
NOT_YET_RECRUITINGWarsaw, 02-786, Poland
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Yitzhak Shamir Medical Center
NOT_YET_RECRUITINGẔerifin, 7033001, Israel
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Zhongshan Hospital Affiliated to Xiamen University
NOT_YET_RECRUITINGXiamen, 361000, China
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Óbudai Egészségügyi Centrum
NOT_YET_RECRUITINGBudapest, 1036, Hungary
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Conditions
Explore the condition pages connected to this study.