CRISPR breakthrough trial targets incurable autoimmune diseases

NCT ID NCT06925542

Summary

This early-stage study is testing a new treatment called CTX112 for adults with severe autoimmune diseases like lupus, scleroderma, and inflammatory muscle disease that haven't responded to standard therapies. The treatment uses genetically modified immune cells from healthy donors, edited with CRISPR technology to target specific disease-causing cells. Researchers will test different doses to evaluate safety and see if the treatment shows early signs of reducing disease activity.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site 1

    RECRUITING

    St Louis, Missouri, 63130, United States

  • Research Site 2

    RECRUITING

    Chicago, Illinois, 63110, United States

  • Research Site 3

    RECRUITING

    Hanover, 30625, Germany

  • Research Site 4

    RECRUITING

    Redwood City, California, 94063, United States

  • Research Site 5

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • Research Site 6

    RECRUITING

    Boston, Massachusetts, 02118, United States

  • Research Site 7

    NOT_YET_RECRUITING

    Augsburg, 86156, Germany

  • Research Site 8

    RECRUITING

    Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.