CRISPR-Edited cells target devastating autoimmune diseases in groundbreaking trial

NCT ID NCT06925542

Summary

This early-stage study is testing whether genetically modified immune cells can help control severe autoimmune diseases that haven't responded to standard treatments. Researchers are using CRISPR gene editing to create 'off-the-shelf' immune cells from healthy donors that target a specific protein involved in these diseases. The study will first check if the treatment is safe and look for early signs that it might reduce disease activity in adults with lupus, scleroderma, or inflammatory muscle diseases.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site 1

    RECRUITING

    St Louis, Missouri, 63130, United States

  • Research Site 2

    RECRUITING

    Chicago, Illinois, 63110, United States

  • Research Site 3

    RECRUITING

    Hanover, 30625, Germany

  • Research Site 4

    RECRUITING

    Redwood City, California, 94063, United States

  • Research Site 5

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • Research Site 6

    RECRUITING

    Boston, Massachusetts, 02118, United States

  • Research Site 7

    NOT_YET_RECRUITING

    Augsburg, 86156, Germany

  • Research Site 8

    RECRUITING

    Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.