Eczema cream showdown: steroid vs Non-Steroid in kids

NCT ID NCT07537751

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two creams for mild to moderate eczema in 40 children aged 1-12. One cream was a steroid (fluticasone), the other a non-steroid (crisaborole). Both were applied twice daily for 6 weeks, then twice weekly for 12 weeks if the skin improved a lot. Both treatments worked well; the steroid worked faster, but the non-steroid showed a trend toward keeping eczema away longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Crisaborole 2% ointment and fluticasone propionate 0.05% cream

What this could lead to

If successful, this could show that crisaborole is a good non-steroid option for children with eczema, possibly with fewer relapses than steroid creams.

What could go wrong

This was a small, completed trial with only 40 children, so results may not apply to all patients. The trend toward fewer relapses with crisaborole needs confirmation in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atopic eczema Eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Medicine, Kafr Elsheikh University

    Kafr ash Shaykh, Kafr el-Sheikh Governorate, Egypt