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Could a daily creatine drink boost postpartum energy and brainpower?

NCT ID NCT07795853

Symptom relief Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

Researchers are testing whether taking creatine monohydrate daily for four weeks helps postpartum women improve exercise performance, recover faster after workouts, and sharpen thinking. The trial compares two doses, 5 grams and 10 grams per day, in 40 women who are 6 weeks to 12 months after giving birth. Participants mix the supplement with water, and a small group also undergoes brain scans to measure creatine levels. The goal is to see if this common supplement can ease some of the physical and mental fatigue new mothers often face.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Creatine monohydrate taken daily mixed with water
What this could lead to
If it works, creatine could become a simple daily supplement to help new mothers recover from exercise and think more clearly during the postpartum period.
What could go wrong
This is a small, early trial with only 40 participants, so results may not apply to all women. Creatine can cause stomach upset or weight gain, and the higher dose may not add extra benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 6 weeks -12 months postpartum * Body mass index of 18.5-34.9 kg/m2 * Cleared to resume physical activity Exclusion Criteria: * Experienced a musculoskeletal injury, excluding a Cesarean delivery,within the past three months that inhibits participation in the study. * Has chronic kidney disease, liver disease, chronic obstructive pulmonary disease, or cancer * Currently using medications that may directly impact the primary outcomes including: diuretics and corticosteroids). * Has uncontrolled hypertension or diabetes, or has recently started medication, without a stable dose for 3 consecutive months. * Currently using creatine monohydrate or other performance-enhancing supplements * Has a self-identified or clinically diagnosed eating disorder * Taking or having supplemented with creatine monohydrate in the last 28-days * Medical contradictions for physical exercise * Has participated in another clinical trial within 4-weeks prior to enrollment that in the opinion of the PI would influence the results. * Has severely impaired hearing or speech or inability to speak English. * Unwilling or unable to comply with the study protocol, including abstaining from caffeine, tobacco, alcohol, and physical activity before testing days. * Is currently pregnant. * Has a known allergy to the transducer gel used for the ultrasound * Has a known allergy to creatine monohydrate

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post partum Women

How to take part

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  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    1 site. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

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Contacts and locations

Locations

  • Applied Physiology Laboratory

    Chapel Hill, North Carolina, 27599, United States

    Contact Email: •••••@•••••

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