New hope for older leukemia patients: experimental drug combo enters trial
NCT ID NCT05260528
First seen Apr 06, 2026 · Last updated May 13, 2026 · Updated 7 times
Summary
This study compares a new drug, CPX-351, to standard chemotherapy in 248 adults aged 50 and older with newly diagnosed acute myeloid leukemia (AML) that is at intermediate or high risk. The goal is to see if CPX-351 leads to deeper remission with less remaining cancer cells after the first round of treatment. Participants will be randomly assigned to receive either CPX-351 or standard chemo, and their response will be measured using sensitive lab tests.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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CH Avignon
RECRUITINGAvignon, France
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CH de Roubaix
RECRUITINGRoubaix, France
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CHR Metz-Thionville Site Mercy
RECRUITINGMetz, France
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CHR Orléans
RECRUITINGOrléans, France
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CHRU Jean Minjoz
RECRUITINGBesançon, France
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CHU Amiens Picardie site Sud
RECRUITINGAmiens, France
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CHU Estaing
RECRUITINGClermont-Ferrand, France
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CHU Henri Mondor
RECRUITINGCréteil, France
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CHU d'Angers
NOT_YET_RECRUITINGAngers, France
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CHU de Bordeaux
RECRUITINGPessac, France
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CHU de Limoges
RECRUITINGLimoges, France
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CHU de Nantes
NOT_YET_RECRUITINGNantes, France
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CHU de Nice
RECRUITINGNice, France
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CHU de Saint Etienne
RECRUITINGSaint-Priest-en-Jarez, France
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CHU de Toulouse
RECRUITINGToulouse, France
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Centre Antoine Lacassagne
NOT_YET_RECRUITINGNice, France
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Centre Henri Becquerel
RECRUITINGRouen, France
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Centre Hospitalier Sud Francilien (CHSF)
RECRUITINGCorbeil-Essonnes, France
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Centre Hospitalier de Béziers
RECRUITINGBéziers, France
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Centre Hospitalier de Versailles, Site André Mignot
RECRUITINGLe Chesnay, France
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Groupe hospitalier de la région de Mulhouse et Sud-Alsace, Hôpital Emile Muller
RECRUITINGMulhouse, France
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Hopital Bretonneau
RECRUITINGTours, France
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Hopital Lyon Sud
RECRUITINGPierre-Bénite, France
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Hopital Necker
RECRUITINGParis, France
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Hoptial de la Conception APHM
RECRUITINGMarseille, France
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Hôpital Avicenne APHP
RECRUITINGBobigny, France
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Hôpital Claude HURIEZ, CHU Lille
RECRUITINGLille, France
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Hôpital Saint-Antoine
RECRUITINGParis, France
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Hôpital Saint-Louis
RECRUITINGParis, France
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Hôpital d'Instruction des Armée (HIA)
RECRUITINGClamart, France
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Hôpital de la Pitié Salpêtrière
RECRUITINGParis, France
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Institut Gustave Roussy
RECRUITINGVillejuif, France
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Institut Paoli Calmettes
RECRUITINGMarseille, France
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Institut d'hématologie de Basse Normandie (IHBN)
RECRUITINGCaen, France
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Institut de cancérologie du Gard
RECRUITINGNîmes, France
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Conditions
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