New drug CPO301 targets tough cancers in early trial
NCT ID NCT05948865
First seen Mar 24, 2026 · Last updated May 16, 2026 · Updated 7 times
Summary
This early-phase study tests CPO301, a drug that delivers chemotherapy directly to cancer cells, in adults with advanced solid tumors (e.g., lung, breast, colorectal) that have stopped responding to standard treatments. The main goals are to find a safe dose and check for early signs of tumor shrinkage. About 132 participants will receive CPO301 by IV every 3 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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AdventHealth Cancer Institute
RECRUITINGCelebration, Florida, 34747, United States
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Cross Cancer Institute
RECRUITINGEdmonton, Alberta, T6G 1Z2, Canada
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Dartmouth Hitchcock Medical Center
RECRUITINGLebanon, New Hampshire, 03756, United States
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Florida Cancer Specialists
RECRUITINGSarasota, Florida, 34232, United States
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Fox Chase Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19111, United States
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Hoag Memorial Hospital Presbyterian
RECRUITINGNewport Beach, California, 92658, United States
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Juravinski Cancer Centre
RECRUITINGHamilton, Ontario, L8V 5C2, Canada
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NEXT Dallas
RECRUITINGDallas, Texas, 75039, United States
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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Princess Margaret Cancer Centre - University Health Network
RECRUITINGToronto, Ontario, M5G 2M9, Canada
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SCRI Oncology Partners
RECRUITINGNashville, Tennessee, 37203, United States
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Sarah Cannon Research Institute (SCRI) at HealthONE
RECRUITINGDenver, Colorado, 80218, United States
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UCLA Hematology/Oncology - Santa Monica
RECRUITINGSanta Monica, California, 90404, United States
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USC Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
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Conditions
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