Transplant patients get stronger COVID protection by temporarily lowering immune drugs
NCT ID NCT05077254
First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 14 times
Summary
This study looked at 48 kidney and liver transplant recipients who had a weak antibody response after their initial COVID-19 vaccines. Researchers gave everyone an extra mRNA booster shot and randomly assigned some to temporarily reduce their immunosuppressive medications. The goal was to see if lowering immune suppression could boost antibody levels without causing organ rejection or serious side effects.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Emory Healthcare
Atlanta, Georgia, 30322, United States
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Houston Methodist
Houston, Texas, 77030, United States
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Johns Hopkins Institute for Clinical and Translational Research: Broadway Adult Outpatient Clinical Research Unit
Baltimore, Maryland, 21287, United States
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Mt. Sinai Hospital
New York, New York, 10029, United States
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NYU Langone Transplant Institute
New York, New York, 10016, United States
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Northwestern University
Evanston, Illinois, 60208, United States
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Ochsner Health
New Orleans, Louisiana, 70121, United States
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University of California San Francisco Health
San Francisco, California, 94143, United States
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University of California, San Diego
San Diego, California, 92093, United States
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University of Illinois Health
Chicago, Illinois, 60612, United States
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University of Iowa Hospitals
Iowa City, Iowa, 52242, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15260, United States
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University of Wisconsin-Madison
Madison, Wisconsin, 53706, United States
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Weill Cornell Medicine
New York, New York, 10065, United States
Conditions
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