New drug AZD7442 tested in hospitalized COVID-19 patients

NCT ID NCT04315948

Completed Disease control Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen May 21, 2026 · Last updated Jun 16, 2026 · Updated 4 times

Summary

This study tested whether adding the drug AZD7442 to standard care helps hospitalized adults with COVID-19 recover faster. About 1,500 participants received either the drug or a placebo. The main goal was to see how their symptoms changed over time, from being able to do normal activities to needing breathing support.

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Contacts and locations

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Locations

AP-HP Hôpital Bicêtre

Le Kremlin-Bicêtre, 94270, France
APHP - Hôpital Bichat Claude Bernard

Paris, 75018, France
APHP - Hôpital Cochin

Paris, 75014, France
APHP - Hôpital Lariboisière

Paris, 75010, France
APHP - Hôpital Necker

Paris, 75015, France
APHP - Hôpital Saint Antoine

Paris, 75012, France
APHP - Hôpital Saint Louis

Paris, 75010, France
APHP - Hôpital Tenon

Paris, 75020, France
APHP - Hôpital Universitaire Pitié Salpêtrière

Paris, 75013, France
APHP - hôpital Henri-Mondor

Créteil, 94010, France
APHP- Hôpital Européen Georges-Pompidou

Paris, 75015, France
Akershus Unniversity Hospital

Oslo, Norway
CH Bretagne Atlantique

Vannes, 56000, France
CH Bretagne Atlantique

Vannes, France
CH Cornouaille

Quimper, France
CHU APHP Ambroise-Paré

Boulogne-Billancourt, France
CHU Nîmes

Nîmes, France
CHU Poitiers

Poitiers, France
CHU de Reims

Reims, 51100, France
CHULN- Hospital de Santa Maria

Lisbon, Portugal
Centre Hospitalier Andrée Rosemon

Cayenne, 97306, France
Centre Hospitalier Annecy Genevois

Épagny, 74370, France
Centre Hospitalier Luxembourg

Luxembourg, L-1210, Luxembourg
Centre Hospitalier Regional Metz-Thionville

Ars-Laquenexy, 57085, France
Centre Hospitalier Régional Universitaire de Besançon

Besançon, 25000, France
Centre Hospitalier Régional Universitaire de Lille

Lille, 59000, France
Centre Hospitalier Régional Universitaire de Strasbourg

Strasbourg, 67000, France
Centre Hospitalier Régional et Universitaire de Nancy

Nancy, 54000, France
Centre Hospitalier Universitaire Amiens-Picardie

Amiens, 80054, France
Centre Hospitalier Universitaire Dijon-Bourgogne

Dijon, 21000, France
Centre Hospitalier Universitaire de Bordeaux

Bordeaux, 33000, France
Centre Hospitalier Universitaire de Martinique

Fort de France, 97261, France
Centre Hospitalier Universitaire de Montpellier

Montpellier, 34000, France
Centre Hospitalier Universitaire de Nantes

Nantes, 44000, France
Centre Hospitalier Universitaire de Rennes

Rennes, 35033, France
Centre Hospitalier Universitaire de Saint Etienne

Saint-Etienne, 42055, France
Centre Hospitalier Universitaire de Toulouse

Toulouse, 31000, France
Centre Hospitalier Universitaire de Toulouse

Toulouse, 31300, France
Centre Hospitalier Universitaire de Tours

Tours, 37000, France
Centre Hospitalier de Tourcoing

Tourcoing, 59208, France
Centre Hospitalo-Universitaire de Grenoble

La Tronche, 38700, France
Centre Hospitalo-Universitaire de Nice

Nice, 06000, France
Centro Hospitalar Universitário de São João, EPE

Porto, Portugal
Evaggelismos General Hospital

Athens, Greece
General University Hospital of Patras

Pátrai, Greece
Groupe Hospitalier de la Région de Mulhouse Sud Alsace

Mulhouse, 68100, France
Hopital DELAFONTAINE

Saint-Denis, 93200, France
Hospices Civil

Colmar, France
Hospices Civils de Lyon

Lyon, 69000, France
Hospital de Cascais

Cascais, Portugal
Hôpital Erasme - Cliniques universitaires de Bruxelles

Brussels, 1070, Belgium
Hôpital La Citadelle

Liège, 4000, Belgium
Hôpital Paris Saint-Joseph et Marie Lannelongue

Paris, 75014, France
Hôpital Saint Luc

Brussels, 1200, Belgium
Hôpital d'Instruction des Armées BEGIN

Saint-Mandé, 94160, France
Hôpitaux Robert Schuman

Luxembourg, L-2450, Luxembourg
Kepler Universitätsklinikum Linz

Linz, Austria
Landeskrankenhaus Salzburg Universitätsklinikum der Paracelsus Medizinischen Privatuniversität

Salzburg, 5020, Austria
Lovisenberg Diaconal Hospital

Oslo, Norway
Medizinische Universität Innsbruck

Innsbruck, 6020, Austria
Oslo University Hospital

Oslo, Norway
Pôle Hospitalier Jolimont / site de Mons-Warquignies

Mons, Belgium

Conditions

Explore the condition pages connected to this study.

CORONA VIRUS INFECTION