New nasal COVID vaccine could replace needles

NCT ID NCT07416539

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing a new nasal spray vaccine called COV2 against COVID-19. Twenty healthy adults who have already had at least two COVID-19 shots will receive two doses of one of two formulations. The study aims to check if the vaccine is safe and whether it boosts the body's immune defenses against the Omicron BA.5 variant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

COV2 vaccine (nasal spray, adenoviral vector-based)

What this could lead to

If successful, this could lead to a needle-free COVID-19 vaccine that may be easier to administer and could boost immunity against variants.

What could go wrong

This is a very early Phase 1 trial with only 20 participants, so safety and immune response are still unproven. The vaccine may not work as hoped or could cause unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19 prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kuopio University Hospital, ENT policlinic

    RECRUITING

    Kuopio, Northern Savonia, 70210, Finland

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••