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A simple breathing maneuver may help ventilator patients wean faster

NCT ID NCT07722260

Symptom relief Sponsor: [email protected] Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This trial tests whether cough augmentation techniques — using the ventilator to increase lung volume and promote coughing — can help critically ill, intubated patients successfully wean off mechanical ventilation. The study includes 88 adult patients of both sexes, excluding those with facial trauma or a tracheostomy tube. The main goal is to see if these techniques lead to successful extubation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cough augmentation techniques (lung volume recruitment maneuver via mechanical ventilation)
What this could lead to
If effective, these techniques could help critically ill patients breathe on their own sooner, reducing time on ventilators and related complications.
What could go wrong
This is a small, early-stage trial. The techniques may not improve weaning success and could cause discomfort or lung injury in some patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 88 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * adult intubated patients * both sex Exclusion Criteria: * patient with facial trauma * patient with tracheostomy tube

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Physiological parameters

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

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    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Faculty of Nursing, Damanhur University

    RECRUITING

    Damanhūr, Egypt

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