New drug tested to halt scarring in fatty liver disease

NCT ID NCT05364931

Completed Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study tested whether a drug called cotadutide is safe and can help people with a type of fatty liver disease called NASH, which causes liver scarring. Fifty-four adults with confirmed liver scarring received either the drug or a placebo for about six months. The main goals were to check for side effects and see if the drug could reduce liver damage.

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Contacts and locations

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Locations

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Tucson, Arizona, 85712, United States
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Canoga Park, California, 91303, United States
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Gilroy, California, 95020, United States
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Sacramento, California, 95821, United States
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Englewood, Colorado, 80113, United States
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Bradenton, Florida, 34208, United States
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Homestead, Florida, 33032, United States
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Jacksonville, Florida, 32216, United States
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Miami, Florida, 33175, United States
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Miami, Florida, 33176, United States
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Winter Park, Florida, 32789, United States
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Munster, Indiana, 46321, United States
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Houma, Louisiana, 70363, United States
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Marrero, Louisiana, 70006, United States
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Marrero, Louisiana, 70072, United States
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Shreveport, Louisiana, 71105, United States
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Ann Arbor, Michigan, 48109, United States
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Las Vegas, Nevada, 89104, United States
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Las Vegas, Nevada, 89109, United States
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Lawrence, New Jersey, 08648, United States
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Warren Township, New Jersey, 07059, United States
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Morehead City, North Carolina, 28557, United States
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Chattanooga, Tennessee, 37421, United States
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Arlington, Texas, 76012, United States
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Austin, Texas, 78745, United States
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Dallas, Texas, 75230, United States
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Lewisville, Texas, 75057, United States
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San Antonio, Texas, 78215, United States
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Ogden, Utah, 84403, United States
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CABA, C1056ABJ, Argentina
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Heidelberg, 3084, Australia
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Kogarah, 2217, Australia
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Meadowbrook, 4131, Australia
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Melbourne, 3004, Australia
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Westmead, 2145, Australia
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Vienna, 1030, Austria
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Vienna, 1130, Austria
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London, Ontario, N6A 5A5, Canada
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Terrebonne, Quebec, J6X 4P7, Canada
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Montpellier, 34090, France
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Paris, 75651, France
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Dresden, 01307, Germany
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Konstanz, 78464, Germany
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Athens, 12462, Greece
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Ioannina, 45500, Greece
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Haifa, 34362, Israel
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Jerusalem, 91031, Israel
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Nahariya, 22100, Israel
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Petah Tikva, 49100, Israel
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Tel Aviv, 64239, Israel
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Tel Litwinsky, 52621, Israel
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Catania, 95100, Italy
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Foggia, 71100, Italy
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Milan, 20127, Italy
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Roma, 00100, Italy
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Roma, 00161, Italy
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Rozzano, 20089, Italy
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San Giovanni Rotondo, 71013, Italy
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Chiba, 260-8677, Japan
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Fukui-shi, 918-8503, Japan
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Gifu, 500-8513, Japan
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Hiroshima, 734-8551, Japan
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Kawasaki-shi, 215-0026, Japan
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Kawasaki-shi, 216-8511, Japan
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Kure-shi, 737-0023, Japan
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Osaka, 637086, Japan
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Saga, 849-8501, Japan
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Sapporo, 062-0921, Japan
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Sendai, 980-0873, Japan
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Shinjuku-ku, 160-0023, Japan
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Suita-shi, 564-0013, Japan
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Takasaki-shi, 370-0829, Japan
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Toon-shi, 791-0281, Japan
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Yokohama, 236-0004, Japan
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Yokohama, 245-8575, Japan
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Kuala Lumpur, 56000, Malaysia
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Kuala Lumpur, 59100, Malaysia
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Malacca, 75400, Malaysia
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Seremban, 70300, Malaysia
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Auckland, 2025, New Zealand
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Christchurch, 8011, New Zealand
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Grafton, 1023, New Zealand
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Plumstead, 7800, South Africa
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Busan, 49241, South Korea
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Gangwon-do, 26426, South Korea
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Junggu, 41944, South Korea
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Seoul, 03080, South Korea
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Seoul, 04763, South Korea
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Seoul, 06351, South Korea
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A Coruña, 15006, Spain
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Almería, 04009, Spain
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Lleida, 25198, Spain
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Madrid, 28046, Spain
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Málaga, 29010, Spain
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Seville, 41013, Spain
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Kaohsiung City, 80756, Taiwan
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Tainan, 70403, Taiwan
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Taipei, 110, Taiwan
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Taipei, 11217, Taiwan
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Taipei, 114, Taiwan
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Bangkok, 10330, Thailand
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Bangkok, 10400, Thailand
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Bangkok, 10700, Thailand
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Hat Yai, 90110, Thailand
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Khon Kaen, 40002, Thailand
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Ankara, 06800, Turkey (Türkiye)
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Istanbul, 34093, Turkey (Türkiye)
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Aberdeen, AB25 2ZN, United Kingdom
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Glasgow, G51 4LB, United Kingdom
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Ipswich, IP4 5PD, United Kingdom
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Liverpool, L1 9ED, United Kingdom
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London, EN1 1LJ, United Kingdom
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Preston, PR2 9QB, United Kingdom
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Rochdale, OL11 4AU, United Kingdom
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Sheffield, S2 5FX, United Kingdom

Conditions

Explore the condition pages connected to this study.

NON-CIRRHOTIC NON-ALCOHOLIC STEATOHEPATITIS WITH FIBROSIS