Skincare breakthrough? new study tests niacinamide creams for dark spots in black women

NCT ID NCT07618572

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a daily skincare routine with niacinamide and bioceramides can reduce facial dark spots (post-inflammatory hyperpigmentation) and improve self-esteem and quality of life in 60 Black women with darker skin tones. Participants will use a cleanser, moisturizer, serum, and sunscreen for 12 weeks, and doctors will track changes in pigmentation and well-being through photos and questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Niacinamide and Bioceramide-Based Skincare Regimen
What this could lead to
If it works, this could offer a simple, non-prescription skincare routine to reduce facial dark spots and boost self-esteem in Black women.
What could go wrong
This is a small, early-stage study with only 60 participants and no comparison group, so results may not apply broadly. The improvement may be modest or temporary.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Israelita Albert Einstein

    RECRUITING

    São Paulo, São Paulo, 05652-900, Brazil

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