Skincare breakthrough? new study tests niacinamide creams for dark spots in black women

NCT ID NCT07618572

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a daily skincare routine with niacinamide and bioceramides can reduce facial dark spots (post-inflammatory hyperpigmentation) and improve self-esteem and quality of life in 60 Black women with darker skin tones. Participants will use a cleanser, moisturizer, serum, and sunscreen for 12 weeks, and doctors will track changes in pigmentation and well-being through photos and questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Niacinamide and Bioceramide-Based Skincare Regimen

What this could lead to

If it works, this could offer a simple, non-prescription skincare routine to reduce facial dark spots and boost self-esteem in Black women.

What could go wrong

This is a small, early-stage study with only 60 participants and no comparison group, so results may not apply broadly. The improvement may be modest or temporary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hyperpigmentation hyperpigmentation of the skin

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Israelita Albert Einstein

    RECRUITING

    São Paulo, São Paulo, 05652-900, Brazil

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••