Spit test could spot hormone disorder in adrenal tumor patients

NCT ID NCT07350031

First seen Jan 23, 2026 · Last updated May 25, 2026 · Updated 18 times

Summary

This study looked at whether measuring cortisol in saliva works as well as the standard blood test to diagnose high cortisol levels (hypercortisolism) in people with adrenal incidentalomas—non-cancerous tumors found by chance on scans. About 100 patients and 100 healthy adults provided saliva and blood samples after taking a low-dose steroid pill. The goal was to see if the simpler, non-invasive saliva test could reliably replace the blood test for diagnosis.

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