Steroids may ease painful skin side effect of breast cancer chemo
NCT ID NCT07362914
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial is testing whether the corticosteroid dexamethasone can reduce hand-foot syndrome—a painful skin reaction—caused by liposomal doxorubicin chemotherapy in breast cancer patients. 182 participants will receive either high-dose, standard-dose, or no dexamethasone alongside their chemo. The goal is to see if steroids can make treatment more tolerable without affecting cancer control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dexamethasone (a corticosteroid)
- What this could lead to
- If it works, this could offer a simple way to prevent painful hand-foot skin reactions during chemotherapy, improving quality of life for breast cancer patients.
- What could go wrong
- This is a phase 3 trial, but it is still early to know if the benefit is real. Corticosteroids have side effects like infection risk and high blood sugar, and the study is relatively small (182 people).
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Fudan University Shanghai Cancer Center
RECRUITINGShanghai, Shanghai Municipality, 200032, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Chest-Injected drug drain Cancer's fluid trap?
- A dab of gel on the breathing tube might spare surgery patients a sore throat — a trial puts it to the test.
- Can a deeper nerve block ease pain after breast surgery?
- Does breast cancer radiation harm a key immune gland? a study investigates
- A web program may ease the emotional toll of chemotherapy hair loss
- Can 3D breast imaging spot more dangerous cancers than standard mammograms?