Why Won't dry eye heal? scientists check nerve damage in GVHD patients
NCT ID NCT04700657
First seen Jun 24, 2026 · Last updated Aug 13, 2026 · Updated 3 times
Summary
This study explores whether nerve damage in the cornea causes stubborn dry eye in people with ocular graft-versus-host disease (GVHD), a complication of stem cell transplants. Researchers will measure corneal sensation in 30 GVHD patients and compare it to healthy controls. The goal is to understand why symptoms persist and how nerve health relates to other signs of dry eye.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If this study finds a link between corneal nerve damage and stubborn dry eye in GVHD, it could point toward new ways to treat or manage this condition.
- What could go wrong
- This is a small, early observational study with only 30 participants, so results may not apply to everyone. It is designed to gather knowledge, not test a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Glick Eye Institute - Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States