Eye transplant breakthrough? Cross-Linked donor tissue may prevent rejection

NCT ID NCT06753916

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 31 times

Summary

This study tests whether treating donor corneal tissue with a special cross-linking process before transplant can make it stronger and less likely to be rejected. The trial involves 96 adults who need a high-risk cornea transplant due to blood vessel growth in the eye. Researchers will monitor safety and check if the treated tissue helps prevent graft failure over two years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Cincinnati Eye Institute

    RECRUITING

    Cincinnati, Ohio, 45242, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University - Duke Eye Center

    RECRUITING

    Durham, North Carolina, 27705, United States

    Contact

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kansas City Eye Clinic

    RECRUITING

    Overland Park, Kansas, 66204, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts Eye and Ear

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Mid-Atlantic Cornea Consultant

    NOT_YET_RECRUITING

    Towson, Maryland, 21204, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Price Vision Group

    RECRUITING

    Indianapolis, Indiana, 46260, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of California Los Angeles - Doris Stein Eye Research Center

    NOT_YET_RECRUITING

    Los Angeles, California, 90095, United States

    Contact

  • University of California Irvine - Gavin Herbert Eye Institute

    NOT_YET_RECRUITING

    Irvine, California, 92617, United States

    Contact

  • University of California San Francisco - Wayne and Gladys Valley Center for Vision

    NOT_YET_RECRUITING

    San Francisco, California, 94158, United States

    Contact Email: •••••@•••••

    Contact

  • University of Miami - Bascom Palmer Eye Institute

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • University of Michigan - Kellogg Eye Center

    RECRUITING

    Ann Arbor, Michigan, 48015, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Wake Forest Baptist Eye Center

    NOT_YET_RECRUITING

    Bermuda Run, North Carolina, 27006, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.