New Natural-Material heart valve could fix tricuspid trouble

NCT ID NCT05742906

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing a new replacement valve for the tricuspid valve, which controls blood flow in the heart. The valve is made from natural materials and is designed to treat tricuspid valve disease in both adults and children. Researchers want to see if the valve can be safely implanted and if it works well for at least 12 months. Participants will have the valve implanted and be followed for up to 5 years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cor TRICUSPID ECM Valve (a replacement heart valve made from natural materials)

What this could lead to

If successful, this could provide a safe and effective new option for replacing a diseased tricuspid valve, potentially improving heart function and quality of life.

What could go wrong

This is a pivotal study but still early in testing. The device may not work as expected, and risks include infection, valve failure, or need for additional procedures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

tricuspid valve disorder tricuspid valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Irving Medical Center/New York Presbyterian

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St Francis Hospital

    RECRUITING

    Indianapolis, Indiana, 46237, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact