Cord blood cells join fight against stubborn transplant complication

NCT ID NCT04744116

First seen Nov 10, 2025 · Last updated Apr 25, 2026 · Updated 13 times

Summary

This study tests whether adding special cells from donated cord blood to a standard drug (ruxolitinib) can better control severe graft-versus-host disease (GVHD) that hasn't responded to steroids. GVHD is a serious complication where donor immune cells attack the patient's body after a stem cell transplant. The trial involves 24 participants aged 12-80 and aims to see if the combination improves response and reduces side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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