Head-to-Head COPD drug showdown: which keeps patients out of hospital?

NCT ID NCT04069312

Summary

This large, 6-year study directly compared two existing medications—roflumilast and azithromycin—to see which is better at preventing severe COPD flare-ups that lead to hospitalization or death. It enrolled over 1,000 adults with severe COPD who had recently been hospitalized. The goal was to provide clearer guidance for doctors and patients on the best long-term treatment strategy to control the disease.

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Contacts and locations

Locations

  • Baylor Scott & White (BSW) Health-North

    Dallas, Texas, 75246, United States

  • Baystate Health

    Springfield, Massachusetts, 01199, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Duke

    Durham, North Carolina, 27705, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21224, United States

  • Kaiser Permanente

    Portland, Oregon, 97227, United States

  • Lenox Hill Hospital/Northwell Health

    New York, New York, 10075, United States

  • Mount Sinai

    New York, New York, 10029, United States

  • NorthShore Hospital

    Glenview, Illinois, 60026, United States

  • Northern Westchester Hospital/Northwell Health

    Mount Kisco, New York, 10549, United States

  • Northwestern

    Chicago, Illinois, 60611, United States

  • Ochsner Medical Center

    New Orleans, Louisiana, 70121, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • Providence Health and Services

    Spokane, Washington, 99204, United States

  • Temple University Hospital

    Philadelphia, Pennsylvania, 19140, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Alabama

    Birmingham, Alabama, 35233, United States

  • University of Arizona

    Tucson, Arizona, 85734, United States

  • University of California, Davis Health

    Sacramento, California, 95817, United States

  • University of Illinois, Chicago

    Chicago, Illinois, 60612, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Kansas

    Kansas City, Kansas, 66160, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Missouri, Kansas City

    Kansas City, Missouri, 64108, United States

  • University of North Carolina, School of Medicine

    Chapel Hill, North Carolina, 27599, United States

  • University of Pittsburg Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Vermont

    Burlington, Vermont, 05401, United States

Conditions

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