New shot aims to tame COPD Flare-Ups in former smokers

NCT ID NCT04701983

Completed Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

Summary

This large, completed Phase 3 trial tested whether a new injectable drug called itepekimab could help control Chronic Obstructive Pulmonary Disease (COPD) in former smokers. The study involved over 1,100 adults with moderate-to-severe COPD who had a history of frequent symptom flare-ups. Participants received either the drug or a placebo injection for up to a year to see if it reduced the rate of these serious breathing attacks and improved lung function.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

ASHA Clinical Research Site Number : 8400408

Hammond, Indiana, 46324, United States
Accellacare Site Number : 8400001

Wilmington, North Carolina, 28401, United States
AdtreMed Site Number : 8400442

Tampa, Florida, 33607, United States
Advance Lung and Sleep Center Site Number : 8400040

Sherman, Texas, 75092, United States
Advanced Clinical Research Site Number : 8400409

Kendall, Florida, 33156, United States
Advanced Pulmonary Research Institute Site Number : 8400455

Loxahatchee Groves, Florida, 33470, United States
Advanced Pulmonary Research Institute of Michigan Site Number : 8400403

Warren, Michigan, 48088, United States
Alpha Clinical Research Georgia Site Number : 8400190

Dunwoody, Georgia, 30350, United States
Antelope Valley Clinical Trials Site Number : 8400003

Northridge, California, 91325, United States
Appalachian Clinical Research Site Number : 8400024

Adairsville, Georgia, 30103, United States
Austin Pulmonary Consultants Site Number : 8400035

Cedar Park, Texas, 78641, United States
Avanza Medical Research Center Site Number : 8400376

Pensacola, Florida, 32503, United States
Beautiful Minds Clinical Research Center Site Number : 8400037

Cutler Bay, Florida, 33157, United States
Benchmark Research Site Number : 8400193

Covington, Louisiana, 70433, United States
Bernstein Clinical Research Center Site Number : 8400014

Cincinnati, Ohio, 45236, United States
Biopharma Informatic - Cardiff Avenue - PPDS Site Number : 8400038

Houston, Texas, 77043-2742, United States
Bogan Sleep Consultants Site Number : 8400181

Columbia, South Carolina, 29201, United States
Broward Pulmonary and Sleep Specialists Site Number : 8400031

Plantation, Florida, 33324, United States
California Research Institute Site Number : 8400400

Huntington Park, California, 90255, United States
Care Access Site Number : 8400276

Boston, Massachusetts, 02110, United States
Care Access Site Number : 8400277

Boston, Massachusetts, 02110, United States
Care Access Site Number : 8400278

Boston, Massachusetts, 02110, United States
Care Access Site Number : 8400280

Boston, Massachusetts, 02110, United States
Care Access Site Number : 8400281

Boston, Massachusetts, 02110, United States
Carolina Research Center Site Number : 8400005

Shelby, North Carolina, 28150, United States
Chandler Clinical Trials (Elite Clinical Network) Site Number : 8400034

Chandler, Arizona, 85286, United States
Clearlake Specialties Site Number : 8400025

Webster, Texas, 77598, United States
Clin Research W Florida Site Number : 8400004

Clearwater, Florida, 33765, United States
Clincove: Plano Primary Care Clinic Site Number : 8400424

Plano, Texas, 75024, United States
Clinical Research of Central PA Site Number : 8400023

DuBois, Pennsylvania, 15801, United States
Clinical Research of Rock Hill Site Number : 8400008

Rock Hill, South Carolina, 29732, United States
Clinrx Research Site Number : 8400021

Carrollton, Texas, 75007, United States
Coastal Medical Research Institute Site Number : 8400044

St. Petersburg, Florida, 33707, United States
Corsicana Medical Research, LLC Site Number : 8400018

Corsicana, Texas, 75110, United States
Covenant Pulmonary Critical Care Site Number : 8400183

Atlanta, Georgia, 30344, United States
DL Research Solutions Inc Site Number : 8400033

Miami, Florida, 33155, United States
DM Clinical Research Site Number : 8400179

Tomball, Texas, 77375, United States
David Kavtaradze MD, Inc. Site Number : 8400029

Cordele, Georgia, 31015, United States
Deluxe Health Center Site Number : 8400188

Miami Lakes, Florida, 33014, United States
Downtown LA Research Center Inc. Site Number : 8400027

Los Angeles, California, 90017, United States
EPW Curesearch Dallas (Advanced Family Medical Care) Site Number : 8400414

Plano, Texas, 75093, United States
East Carolina University Brody School Of Medicine Site Number : 8400022

Greenville, North Carolina, 27834, United States
Exordia Medical Research, Inc. Site Number : 8400041

Fall River, Massachusetts, 02723, United States
Florida Institute for Clinical Research Site Number : 8400013

Orlando, Florida, 32825-4454, United States
Gastonia Pharmaceutical Research Site Number : 8400010

Gastonia, North Carolina, 28054, United States
GenHarp Clinical Solutions Site Number : 8400028

Evergreen Park, Illinois, 60805, United States
Gwinnett Biomedical Research Site Number : 8400007

Lawrenceville, Georgia, 30046, United States
Hannibal Clinic Site Number : 8400383

Hannibal, Missouri, 63401, United States
Hendeson Clinical Trials Site Number : 8400365

Henderson, Nevada, 89052, United States
High Quality Research Site Number : 8400406

Miami, Florida, 33184, United States
Imax Clinical Trials LLC 1 Site Number : 8400419

La Palma, California, 90623, United States
Indago Research and Health Center Site Number : 8400187

Hialeah, Florida, 33012, United States
Innovative Clinical Research Site Number : 8400017

Lafayette, Colorado, 80026, United States
Investigational Site Number : 0320001

CABA, Buenos Aires, C1425BEN, Argentina
Investigational Site Number : 0320002

CABA, Buenos Aires, C1425FVH, Argentina
Investigational Site Number : 0320003

Rosario, Santa Fe Province, S2000DEJ, Argentina
Investigational Site Number : 0320004

Mendoza, 5500, Argentina
Investigational Site Number : 0320005

La Plata, Buenos Aires, B1900BNN, Argentina
Investigational Site Number : 1000001

Sofia, 1233, Bulgaria
Investigational Site Number : 1000002

Sofia, 1407, Bulgaria
Investigational Site Number : 1000003

Stara Zagora, 6001, Bulgaria
Investigational Site Number : 1000004

Sofia, 1233, Bulgaria
Investigational Site Number : 1000005

Dimitrovgrad, 6400, Bulgaria
Investigational Site Number : 1000006

Stara Zagora, 6000, Bulgaria
Investigational Site Number : 1000007

Veliko Tyrnovo, 5000, Bulgaria
Investigational Site Number : 1000008

Vidin, 3700, Bulgaria
Investigational Site Number : 1000009

Sofia, 1756, Bulgaria
Investigational Site Number : 1520001

Santiago, Reg Metropolitana de Santiago, 7500692, Chile
Investigational Site Number : 1520002

Talca, Maule Region, Chile
Investigational Site Number : 1520003

Santiago, Reg Metropolitana de Santiago, 7500571, Chile
Investigational Site Number : 1520004

Santiago, Reg Metropolitana de Santiago, 7750495, Chile
Investigational Site Number : 1520005

Quillota, Región de Valparaíso, 2260877, Chile
Investigational Site Number : 1520006

Santiago, Reg Metropolitana de Santiago, 7500698, Chile
Investigational Site Number : 1520007

Curicó, Maule Region, 3341643, Chile
Investigational Site Number : 1520008

Temuco, La Araucanía, 4781173, Chile
Investigational Site Number : 1520009

Santiago, Reg Metropolitana de Santiago, 7500010, Chile
Investigational Site Number : 1560001

Chengdu, 610041, China
Investigational Site Number : 1560002

Changchun, 130021, China
Investigational Site Number : 1560003

Baotou, 014010, China
Investigational Site Number : 1560004

Beijing, 100020, China
Investigational Site Number : 1560005

Shenyang, 110004, China
Investigational Site Number : 1560006

Guangzhou, 510150, China
Investigational Site Number : 1560007

Xuzhou, 221002, China
Investigational Site Number : 1560008

Hohhot, 010017, China
Investigational Site Number : 1560009

Shanghai, 200433, China
Investigational Site Number : 1560010

Hohhot, 010050, China
Investigational Site Number : 1560012

Changsha, 410011, China
Investigational Site Number : 1560013

Changsha, 410013, China
Investigational Site Number : 1560014

Beijing, China
Investigational Site Number : 1560015

Pingxiang, 337055, China
Investigational Site Number : 1560016

Xi'an, China
Investigational Site Number : 1560017

Hefei, China
Investigational Site Number : 1560019

Wenzhou, 325000, China
Investigational Site Number : 1560020

Shenzhen, 518020, China
Investigational Site Number : 1560022

Hangzhou, 310014, China
Investigational Site Number : 1560023

Nanning, 530021, China
Investigational Site Number : 1560024

Tianjin, 300052, China
Investigational Site Number : 1560025

Guangzhou, 510163, China
Investigational Site Number : 1560026

Yangzhou, 225001, China
Investigational Site Number : 1560027

Jinan, 250014, China
Investigational Site Number : 1560028

Shijiazhuang, 050000, China
Investigational Site Number : 1560029

Wuhan, 430014, China
Investigational Site Number : 1560030

Beijing, 100038, China
Investigational Site Number : 1560031

Nanchang, 330006, China
Investigational Site Number : 1560032

Chongqing, 400038, China
Investigational Site Number : 1560034

Shanghai, 200240, China
Investigational Site Number : 1560035

Nanjing, 210009, China
Investigational Site Number : 1560036

Haikou, 570216, China
Investigational Site Number : 1560039

Hangzhou, China
Investigational Site Number : 1560040

Chengdu, 611130, China
Investigational Site Number : 1560041

Zhanjiang, 524001, China
Investigational Site Number : 1560042

Zhengzhou, 450008, China
Investigational Site Number : 1560043

Shanghai, 200025, China
Investigational Site Number : 1560044

Jinan, 250013, China
Investigational Site Number : 1560045

Shanghai, China
Investigational Site Number : 1560046

Xiangtan, 411100, China
Investigational Site Number : 1560047

Changsha, 410023, China
Investigational Site Number : 1560048

Zhongshan, 528403, China
Investigational Site Number : 1580002

New Taipei City, 220, Taiwan
Investigational Site Number : 1580003

Taipei, 11031, Taiwan
Investigational Site Number : 1580004

Taipei, 10002, Taiwan
Investigational Site Number : 1580005

Kaohsiung City, 807, Taiwan
Investigational Site Number : 1580006

Taichung, 40447, Taiwan
Investigational Site Number : 1580008

Yunlin, Taiwan
Investigational Site Number : 2030001

Jindrichuv Hradec III, 37701, Czechia
Investigational Site Number : 2030002

Prague, 140 46, Czechia
Investigational Site Number : 2030003

Prague, 18200, Czechia
Investigational Site Number : 2030004

Ostrava, 70800, Czechia
Investigational Site Number : 2030005

Praha 5 - Radotin, 15300, Czechia
Investigational Site Number : 2030006

Havlíčkův Brod, 580 01, Czechia
Investigational Site Number : 2680001

Tbilisi, 159, Georgia
Investigational Site Number : 2680002

Tbilisi, 0112, Georgia
Investigational Site Number : 2680003

Tbilisi, 0112, Georgia
Investigational Site Number : 3000001

Ioannina, 455 00, Greece
Investigational Site Number : 3000002

Thessaloniki, 57010, Greece
Investigational Site Number : 3000004

Heraklion, 71500, Greece
Investigational Site Number : 3000005

Athens, 106 76, Greece
Investigational Site Number : 3000006

Athens, 11527, Greece
Investigational Site Number : 3000007

Larissa, 41110, Greece
Investigational Site Number : 3000008

Palaio Faliro, Athens, 17562, Greece
Investigational Site Number : 3480001

Gödöllö, 2100, Hungary
Investigational Site Number : 3480002

Mosonmagyaróvár, 9200, Hungary
Investigational Site Number : 3480003

Pécs, 7635, Hungary
Investigational Site Number : 3480004

Debrecen, 4031, Hungary
Investigational Site Number : 3560001

Kozhikode, 673008, India
Investigational Site Number : 3560002

Coimbatore, 641028, India
Investigational Site Number : 3560003

Nagpur, 441203, India
Investigational Site Number : 3560004

Jaipur, 302039, India
Investigational Site Number : 3560005

Hyderabad, 500 084, India
Investigational Site Number : 3560007

Mumbai, 400078, India
Investigational Site Number : 3760001

Petah Tikva, 49100, Israel
Investigational Site Number : 3760002

Jerusalem, 91120, Israel
Investigational Site Number : 3760003

Jerusalem, 91031, Israel
Investigational Site Number : 3760004

Rehovot, 76100, Israel
Investigational Site Number : 3760006

Kfar Saba, 44281, Israel
Investigational Site Number : 3760007

Tel Aviv, 64239, Israel
Investigational Site Number : 3760008

Haifa, 34362, Israel
Investigational Site Number : 3760009

Ramat Gan, 5266202, Israel
Investigational Site Number : 3800001

Ferrara, 44124, Italy
Investigational Site Number : 3800003

Rozzano, Milano, 20089, Italy
Investigational Site Number : 3800004

Foggia, Apulia, 71122, Italy
Investigational Site Number : 3800005

Catania, 95123, Italy
Investigational Site Number : 3800007

Verona, 37134, Italy
Investigational Site Number : 4800001

Quatre Bornes, 72218, Mauritius
Investigational Site Number : 4840001

Guadalajara, Jalisco, 44100, Mexico
Investigational Site Number : 4840002

Mexico City, Mexico City, 06700, Mexico
Investigational Site Number : 4840003

San Juan del Río, Querétaro, 76800, Mexico
Investigational Site Number : 4840004

Benito Juárez, 03100, Mexico
Investigational Site Number : 4840007

Cuernavaca, Morelos, 62250, Mexico
Investigational Site Number : 4840010

Guadalajara, Jalisco, 44210, Mexico
Investigational Site Number : 4840011

Guadalajara, Jalisco, 44130, Mexico
Investigational Site Number : 4840013

Aguascalientes, 20116, Mexico
Investigational Site Number : 4840014

Oaxaca City, 68000, Mexico
Investigational Site Number : 4840016

Oaxaca City, Oaxaca, 68020, Mexico
Investigational Site Number : 6160001

Bialystok, Podlaskie Voivodeship, 15-044, Poland
Investigational Site Number : 6160002

Ostrowiec Świętokrzyski, Świętokrzyskie Voivodeship, 27-400, Poland
Investigational Site Number : 6160003

Warsaw, Masovian Voivodeship, 02-777, Poland
Investigational Site Number : 6160004

Wroclaw, Lower Silesian Voivodeship, 53-673, Poland
Investigational Site Number : 6420001

Iași, 700732, Romania
Investigational Site Number : 6420002

Cluj-Napoca, 400275, Romania
Investigational Site Number : 6420003

Timișoara, 300134, Romania
Investigational Site Number : 6420005

Bragadiru, 769764, Romania
Investigational Site Number : 6420006

Brasov, 500450, Romania
Investigational Site Number : 6420007

Codlea, 505100, Romania
Investigational Site Number : 6420009

Oradea, 410155, Romania
Investigational Site Number : 6420010

Deva, 330162, Romania
Investigational Site Number : 6420012

Bucaresti, 010192, Romania
Investigational Site Number : 6430001

Moscow, 115093, Russia
Investigational Site Number : 6430002

Moscow, 117546, Russia
Investigational Site Number : 6430003

Moscow, 115280, Russia
Investigational Site Number : 6430005

Saint Petersburg, 194354, Russia
Investigational Site Number : 6430006

Saint Petersburg, 194354, Russia
Investigational Site Number : 7030001

Spišská Nová Ves, 05201, Slovakia
Investigational Site Number : 7030002

Poprad, 058 01, Slovakia
Investigational Site Number : 7030003

Levice, 93401, Slovakia
Investigational Site Number : 7030007

Humenné, 066 01, Slovakia
Investigational Site Number : 7030009

Bardejov, 08501, Slovakia
Investigational Site Number : 7030010

Prešov, 08001, Slovakia
Investigational Site Number : 7030011

Martin, 03659, Slovakia
Investigational Site Number : 8040001

Kyiv, 01033, Ukraine
Investigational Site Number : 8040003

Ivano-Frankivsk, 76018, Ukraine
Investigational Site Number : 8040004

Kyiv, 01023, Ukraine
Investigational Site Number : 8040005

Kyiv, 02091, Ukraine
Investigational Site Number : 8040006

Kharkiv, 61166, Ukraine
Investigational Site Number : 8040007

Ivano-Frankivsk, 76018, Ukraine
Investigational Site Number : 8040008

Kharkiv, 61039, Ukraine
Investigational Site Number : 8040011

Kyiv, 04050, Ukraine
Investigational Site Number : 8260001

London, EC1M 6BQ, United Kingdom
Investigational Site Number : 8260003

Bradford, BD9 6RJ, United Kingdom
Investigational Site Number : 8260004

Portsmouth, Hampshire, PO6 3LY, United Kingdom
Investigational Site Number : 8260010

Wigan, Lancashire, WN6 9EP, United Kingdom
Investigational Site Number : 8260013

Redruth, TR16 4ET, United Kingdom
Investigational Site Number : 8260014

Heston, TW5 9ER, United Kingdom
Investigational Site Number : 8260015

Ashton-under-Lyne, Lancashire, OL69RW, United Kingdom
Investigational Site Number : 8260016

Salford, Manchester, M6 8HD, United Kingdom
Jasper Summit Research Site Number : 8400178

Jasper, Alabama, 35501, United States
MACRO Trials Site Number : 8400030

Los Angeles, California, 90048, United States
Metroplex Pulmonary and Sleep Center Site Number : 8400015

McKinney, Texas, 75069, United States
Midwest Chest Consultants, P.C. Site Number : 8400002

Saint Charles, Missouri, 63301, United States
Modena Allergy + Asthma Site Number : 8400036

La Jolla, California, 92037, United States
My Community Research Center Site Number : 8400347

Miami, Florida, 33155, United States
Noble Clinical Research Site Number : 8400182

Tucson, Arizona, 85704-7876, United States
Northwell Health Site Number : 8400019

Mount Kisco, New York, 10549, United States
PROLIVE MEDICAL RESEARCH Site Number : 8400420

Miami, Florida, 33175, United States
PRX Research Site Number : 8400380

Mesquite, Texas, 75149, United States
Pasadena Center for Medical Research Site Number : 8400043

St. Petersburg, Florida, 33710, United States
Paul Shapero, PC Site Number : 8400016

Bangor, Maine, 04401, United States
Premier Medical Associates Site Number : 8400388

The Villages, Florida, 32159, United States
Premier Pulmonary Critical Care and Sleep Medicine Site Number : 8400440

Denison, Texas, 75020, United States
Pulmonary Associates Site Number : 8400392

Phoenix, Arizona, 85027, United States
REX Clinical Trials Site Number : 8400371

Beaumont, Texas, 77701, United States
Reed Medical Research Site Number : 8400032

Miami, Florida, 33176, United States
Reliant Medical Research Site Number : 8400397

Miami, Florida, 33165, United States
Research Institute of South Florida,Inc Site Number : 8400006

Miami, Florida, 33173, United States
Revival Research Institute, LLC Site Number : 8400191

Dearborn, Michigan, 48126, United States
Santa Clara Family Clinic Site Number : 8400398

Houston, Texas, 77087, United States
Sherman Clinical Research Site Number : 8400009

Sherman, Texas, 75092, United States
Southeastern Research Center Site Number : 8400011

Winston-Salem, North Carolina, 27103, United States
Tellabio International Research Services Site Number : 8400411

Pembroke Pines, Florida, 33025, United States
Texas Tech University Health Sciences Center Site Number : 8400189

El Paso, Texas, 79911, United States
The Lung and Sleep Research Institute of North Texas Site Number : 8400417

North Richland Hills, Texas, 76180, United States
The Methodist Hospital Research Institute Site Number : 8400194

Houston, Texas, 77030, United States
Tucson Clinical Research Institute Site Number : 8400431

Tucson, Arizona, 85712, United States
University of Alabama at Birmingham Site Number : 8400012

Birmingham, Alabama, 34294, United States
University of Miami/Miami VA Medical Center Site Number : 8400026

Miami, Florida, 33125, United States
WellNow Urgent Care and Clinical Research Site Number : 8400378

Schenectady, New York, 12304, United States
WellNow Urgent Care and Research Site Number : 8400039

Springdale, Ohio, 45215, United States
~Alpine Clinical Research Center Site Number : 8400180

Boulder, Colorado, 80301, United States

Conditions

Explore the condition pages connected to this study.

CHRONIC OBSTRUCTIVE PULMONARY DISEASE