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Chemo-Free hope for lymphoma patients: new combo shows promise

NCT ID NCT03474744

Ongoing Disease control Sponsor: Christian Buske Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new chemotherapy-free treatment for marginal zone lymphoma, a slow-growing blood cancer. It combines two drugs, Copanlisib and Rituximab, to see if they can control the disease better than Rituximab alone, while avoiding harsh chemo side effects. The trial includes 36 adults with newly diagnosed or relapsed lymphoma who need treatment but cannot have or have failed local therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Lymphoma, B-Cell, Marginal Zone marginal zone lymphoma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MARGINAL ZONE LYMPHOMA

Contacts and locations

Locations

  • Elblandkliniken Stiftung & Co. KG, Innere Medizin II

    Riesa, 01589, Germany

  • Gemeinschaftspraxis, Fachärzte für Innere Medizin

    Mannheim, 68161, Germany

  • Johanniter GmbH, Johanniter-Krankenhaus

    Bonn, 53113, Germany

  • Kath. Karl-Leisner-Klinikum gGmbH, Betriebsstätte Wilhelm-Anton-Hospital

    Goch, 47574, Germany

  • Kliniken Ostalb Stauferklinikum Schwäbisch Gmünd, Zentrum für Innere Medizin

    Mutlangen, 73557, Germany

  • Klinikum der Universität München, Medizinische Klinik und Poliklinik III

    München, 83177, Germany

  • MVZ Goslar, MVZ Onkologische Kooperation Harz

    Goslar, 38642, Germany

  • Med. Uni Wien AKH, Klinische Abteilung für Onkologie, Innere Medizin I

    Vienna, 1190, Austria

  • Rotes Kreuz Krankenhaus, Klinik für Interdisziplinäre Onkologie

    Kassel, 34121, Germany

  • Sana Klinikum Offenbach GmbH

    Offenbach, 63069, Germany

  • St. Josef-Hospital, Medizinische Klinik I

    Bochum, 44791, Germany

  • University Hospital Ulm

    Ulm, 89081, Germany

  • Universitätsklinik PIUS Hospital, Innere Medizin

    Oldenburg, 26121, Germany

  • Universitätsklinikum Halle, Klinik und Poliklinik für Innere Medizin

    Halle, 06120, Germany

  • Universitätsmedizin Mannheim, III. Medizinische Klinik

    Mannheim, 68167, Germany

  • Universitätsmedizin Rostock

    Rostock, 18051, Germany

  • ÜBAG MVZ Dr. Vehling-Kaiser GmbH

    Landshut, 84036, Germany

  • ÜBAG MVZ Dr. Vehling-Kaiser GmbH Dingolfing

    Dingolfing, 84113, Germany

More trials for these conditions

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