New drug targets Hard-to-Treat cancers with PTEN loss

NCT ID NCT06360588

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 27 times

Summary

This study tests a drug called copanlisib in 22 adults with advanced solid tumors that have lost a protein called PTEN. The drug works by blocking certain enzymes that help cancer cells grow and survive. The main goal is to see if the tumors shrink or stop growing. This is a phase II trial, meaning the drug is already known to be safe and is now being tested for effectiveness in this specific group of patients.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.