Chilling the brain during stroke: could cold saline boost recovery?
NCT ID NCT07232082
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether cooling the brain with cold saline during clot-removal surgery helps people recover from severe strokes. About 322 adults with large strokes will be randomly assigned to get standard care or standard care plus local brain cooling. The main goal is to see if more patients are independent at 90 days after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intra-arterial cold saline infusion
What this could lead to
If it works, this could offer a new way to protect the brain during stroke treatment, potentially leading to better recovery for patients with large strokes.
What could go wrong
This is an early-stage trial with only 322 participants, so results may not apply to everyone. The cooling procedure carries risks like infection or vessel damage, and it may not improve outcomes.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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