Chill out acne: cooling device shows promise in reducing sebum
NCT ID NCT01686841
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This pilot study tested whether cooling the skin with a device (the Zeltiq System) could safely reduce sebum production in 11 young men with acne. The treatment was applied to the upper back, and sebum levels were measured before and after. The goal was to see if a 30% reduction in sebum was possible, which could help control acne. The study focused on safety and feasibility, not on curing acne.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Zeltiq System (cryolipolysis device)
- What this could lead to
- If it works, this could lead to a non-invasive, drug-free way to reduce sebum and improve acne.
- What could go wrong
- This was a very small pilot study with only 11 men, so results may not apply to everyone. The cooling effect on sebum may be temporary or not strong enough to help acne.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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