Could a simple ultrasound replace CT scans for kids with belly injuries?

NCT ID NCT04718441

Completed Diagnosis Sponsor: David Mooney Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether contrast-enhanced ultrasound (CEUS) can accurately find solid organ injuries in children's abdomens after trauma. 68 children aged 8-18 who already had a CT scan showing an injury received an ultrasound with and without a contrast agent called Lumason. The goal was to see if CEUS results matched the CT findings, potentially offering a radiation-free alternative for diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lumason (contrast agent)
What this could lead to: If successful, this could provide a safer, radiation-free way to diagnose abdominal injuries in children, reducing reliance on CT scans.
What could go wrong: This is an early-phase study with only 68 participants, so results may not apply to all children. The accuracy of CEUS may vary depending on injury type and patient factors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Abdominal Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABDOMINAL INJURY

Contacts and locations

Locations

Boston Children's Hospital

Boston, Massachusetts, 02118, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Phoenix Children's Hospital

Phoenix, Arizona, 85016, United States
University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States
University of Utah

Salt Lake City, Utah, 84113, United States

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