Could a simple ultrasound replace CT scans for kids with belly injuries?

NCT ID NCT04718441

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether contrast-enhanced ultrasound (CEUS) can accurately find solid organ injuries in children's abdomens after trauma. 68 children aged 8-18 who already had a CT scan showing an injury received an ultrasound with and without a contrast agent called Lumason. The goal was to see if CEUS results matched the CT findings, potentially offering a radiation-free alternative for diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lumason (contrast agent)

What this could lead to

If successful, this could provide a safer, radiation-free way to diagnose abdominal injuries in children, reducing reliance on CT scans.

What could go wrong

This is an early-phase study with only 68 participants, so results may not apply to all children. The accuracy of CEUS may vary depending on injury type and patient factors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Abdominal Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02118, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of Utah

    Salt Lake City, Utah, 84113, United States