New drip combo aims to stop chemo nausea in kids

NCT ID NCT05872893

Completed Symptom relief Sponsor: Immune Oncology Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tested whether giving a continuous, slow infusion of ondansetron (a common anti-nausea drug) plus dexamethasone (a steroid) could better control nausea and vomiting in children undergoing chemotherapy. The study enrolled 28 children aged 1 day to 18 years with cancer. The goal was to see if this steady delivery method provides longer-lasting relief compared to standard dosing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ondansetron and dexamethasone
What this could lead to: If it works, this could offer a more effective way to manage chemotherapy-induced nausea and vomiting in children, improving their quality of life during treatment.
What could go wrong: This is a small, completed trial with only 28 participants, so results may not apply to all children. The improvement over standard care may be modest, and side effects like allergic reactions are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer childhood malignant neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PEDIATRIC CANCER

Contacts and locations

Locations

Hematology Center named after prof. R. Yeolyan

Yerevan, 0014, Armenia

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