Lifeline drug access extended for rare blood disorder patients

NCT ID NCT05777993

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 20 times

Summary

This study offers ongoing access to the drug mitapivat for 6 adults with pyruvate kinase deficiency, a rare genetic blood condition causing anemia. Participants must have completed a prior Agios-sponsored mitapivat study and be unable to get the drug commercially. The main goal is to monitor safety and side effects while providing continued treatment.

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Contacts and locations

Locations

  • Kyoto Katsura Hospital

    Kyoto, 615-8256, Japan

  • McMaster Centre for Transfusion Medicine McMaster University

    Hamilton, Ontario, L8S3Z5, Canada

  • Toho University - Omori Medical Center

    Ōta-ku, 143-8541, Japan

  • Tohoku University Hospital

    Sendai, Miyagi, 980-8574, Japan

Conditions

Explore the condition pages connected to this study.