Simple socks and gloves may shield cancer patients from Chemo's nerve pain

NCT ID NCT07464769

Not yet recruiting Prevention Sponsor: Region Jönköping County Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether wearing tight compression garments on hands and feet during chemotherapy can prevent nerve damage (peripheral neuropathy) caused by taxane or oxaliplatin drugs. About 358 breast and colorectal cancer patients will be randomly assigned to wear compression garments or not. Researchers will track nerve symptoms during treatment and for up to 5 years after.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: compression garments (class 2)
What this could lead to: If it works, this could offer a simple, drug-free way to prevent painful nerve damage from chemotherapy, helping cancer patients maintain quality of life.
What could go wrong: This is an early-stage study with no blinding, so results may be influenced by patient expectations. The effect may be small or not last long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm colorectal cancer colorectal neoplasm rectal cancer chemotherapy-induced neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIPHERAL NEUROPATHY DUE TO CHEMOTHERAPY

Contacts and locations

Locations

Linköping University

Jönköping, Sweden

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