Can squeezing hands and feet stop chemo nerve pain?

NCT ID NCT05531916

Ongoing Symptom relief Sponsor: Sun Yat-sen University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether wearing pressurized gloves and foot caps during chemotherapy can prevent nerve damage (peripheral neuropathy) caused by the drug paclitaxel. It involves 182 people with nasopharyngeal cancer who have not yet started treatment. Each patient serves as their own control, and the main goal is to see if the compression therapy reduces the severity of nerve-related side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pressurized gloves and foot caps
What this could lead to: If it works, this could offer a simple, drug-free way to prevent painful nerve damage from chemotherapy.
What could go wrong: This is a small, early-stage study with no control group, so results may not be definitive. The device may not reduce nerve damage for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma chemotherapy-induced neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIPN - CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY NASOPHARYNGEAL CARCINOMA

Contacts and locations

Locations

Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, 510060, China

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