Can squeezing hands and feet stop chemo nerve pain?

NCT ID NCT05531916

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether wearing pressurized gloves and foot caps during chemotherapy can prevent nerve damage (peripheral neuropathy) caused by the drug paclitaxel. It involves 182 people with nasopharyngeal cancer who have not yet started treatment. Each patient serves as their own control, and the main goal is to see if the compression therapy reduces the severity of nerve-related side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pressurized gloves and foot caps

What this could lead to

If it works, this could offer a simple, drug-free way to prevent painful nerve damage from chemotherapy.

What could go wrong

This is a small, early-stage study with no control group, so results may not be definitive. The device may not reduce nerve damage for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma chemotherapy-induced neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China