New Heat-Based treatment for hemorrhoids could be as effective as standard surgery

NCT ID NCT06170736

Recruiting now Disease control Sponsor: Centre Hospitalier Departemental Vendee Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two minimally invasive procedures for grade II/III hemorrhoids: radiofrequency ablation (using heat) and Doppler-guided artery ligation with mucopexy (tying off blood vessels). The goal is to see if the newer heat-based method is as good as the standard one at reducing symptoms like pain, bleeding, and prolapse. About 168 adults who need surgery for their hemorrhoids will take part, and the main outcome is failure rate one year after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiofrequency ablation or Doppler-guided hemorrhoidal artery ligation with mucopexy
What this could lead to: If successful, this could show that radiofrequency ablation is as effective as the current standard, offering patients a less invasive option with potentially lower recurrence rates.
What could go wrong: This is a relatively small trial (168 participants) and recurrence is still possible with both procedures. The results may not apply to all patients or settings.

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Conditions

The condition(s) this trial relates to.

hemorrhoid internal hemorrhoid

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GRADE II/III HAEMORRHOIDS HAEMORRHOIDS INTERNAL HAEMORRHOIDS

Contacts and locations

Locations

CHU Limoges
RECRUITING

Limoges, France
Cabinet de Proctologie
NOT_YET_RECRUITING

Saint-Herblain, France
Centre Hospitalier Départemental de Vendée
RECRUITING

La Roche-sur-Yon, France
Centre Hospitalier Interrégional
RECRUITING

Poissy, France
Centre Hospitalier Privé
RECRUITING

Brest, France
Centre Hospitalier Universitaire
RECRUITING

Amiens, France
Centre Hospitalier Universitaire
RECRUITING

Angers, France
Centre Hospitalier Universitaire
RECRUITING

Nantes, France
Centre Hospitalier Universitaire
RECRUITING

Rennes, France
Clinique Jules Verne
RECRUITING

Nantes, France
Clinique de l'Estuaire
RECRUITING

Saint-Nazaire, France
Clinique de la Sauvegarde
RECRUITING

Lyon, France
Clinique du val d'Ouest
RECRUITING

Écully, France
Hôpital Saint Joseph
RECRUITING

Paris, France
Hôpital de la Louvière
RECRUITING

Lille, France
Institut Mutualiste Montsouris
RECRUITING

Paris, France
Maison de Santé Bagatelle
RECRUITING

Bordeaux, 33000, France
hôpital d'Instruction des Armées
RECRUITING

Saint-Mandé, France

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