New hope for kidney cancer patients: which drug combo works best after immunotherapy fails?

NCT ID NCT05012371

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 31 times

Summary

This study compares two treatment options for people with advanced kidney cancer that has spread and worsened after prior immunotherapy. About 90 participants will receive either a combination of two drugs (lenvatinib and everolimus) or a single drug (cabozantinib). The goal is to see which approach better controls cancer growth and improves quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

Conditions

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