Massive new study aims to find best way to save newborns who Can't breathe

NCT ID NCT07150923

Recruiting now Knowledge-focused Sponsor: Children's Hospital of Philadelphia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two training and support strategies to help hospital staff use a breathing device called a supraglottic airway (SA) during newborn resuscitation. Over 36,000 newborns and their care teams across many hospitals will take part. The goal is to see which approach leads to more frequent and earlier use of the SA when a baby needs help breathing, potentially improving outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Supraglottic airway device and implementation strategies (educational materials, local champions, training, starter packs, plus external facilitation)
What this could lead to: If successful, this could identify the most effective way to train hospital staff to use supraglottic airways, potentially improving survival and outcomes for newborns who need breathing help at birth.
What could go wrong: This is an implementation study, not a test of a new treatment. It focuses on how well hospitals adopt a device already in use, so it may not directly lead to new therapies. Results may vary across different hospitals and settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DELIVERY ROOM RESUSCITATION IMPLEMENTATION RESEARCH INFANT, NEWBORN LARYNGEAL MASK AIRWAYS NEONATAL RESUSCITATION POSITIVE PRESSURE VENTILATION SUPRAGLOTTIC AIRWAY

Contacts and locations

Locations

Atrium Health Levine Children's Hospital
RECRUITING

Charlotte, North Carolina, 28203, United States
Cedars-Sinai Medical Center
NOT_YET_RECRUITING

Los Angeles, California, 90048, United States
Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19146, United States
Children's Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States
ChristianaCare
RECRUITING

Newark, Delaware, 19718, United States
Cohen Children's Medical Center
NOT_YET_RECRUITING

Queens, New York, 11040, United States
Good Samaritan Hospital
NOT_YET_RECRUITING

Cincinnati, Ohio, 45220, United States
Hackensack University Medical Center
NOT_YET_RECRUITING

Hackensack, New Jersey, 07601, United States
Hospital of the University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Jacobs Medical Center at University of California San Diego Health
NOT_YET_RECRUITING

San Diego, California, 92037, United States
Lenox Hill Hospital
NOT_YET_RECRUITING

New York, New York, 10075, United States
Lucile Packard Children's Hospital
RECRUITING

Palo Alto, California, 94304, United States
MaineHealth Maine Medical Center
RECRUITING

Portland, Maine, 04102, United States
MaineHealth Mid Coast Hospital
RECRUITING

Brunswick, Maine, 04011, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Nationwide Children's Hospital
NOT_YET_RECRUITING

Columbus, Ohio, 43205, United States
Oklahoma Children's Hospital
NOT_YET_RECRUITING

Oklahoma City, Oklahoma, 73104, United States
Parkland Health
RECRUITING

Dallas, Texas, 75235, United States
Rady Children's NICU at Rancho Springs Medical Center
NOT_YET_RECRUITING

Murrieta, California, 92562, United States
Riley Hospital for Children
NOT_YET_RECRUITING

Indianapolis, Indiana, 46202, United States
Sharp Chula Vista Medical Center
NOT_YET_RECRUITING

Chula Vista, California, 91911, United States
Sharp Grossmont Hospital
NOT_YET_RECRUITING

La Mesa, California, 91942, United States
Sharp Mary Birch Hospital for Women & Newborns
NOT_YET_RECRUITING

San Diego, California, 92123, United States
South Shore University Hospital
NOT_YET_RECRUITING

Bay Shore, New York, 11706, United States
St. John's Children's Hospital
NOT_YET_RECRUITING

Springfield, Illinois, 62701, United States
Texas Children's Hospital
NOT_YET_RECRUITING

Houston, Texas, 77030, United States
Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35294, United States
University of Arkansas for Medical Sciences
RECRUITING

Little Rock, Arkansas, 72205, United States
University of North Carolina at Chapel Hill
NOT_YET_RECRUITING

Chapel Hill, North Carolina, 27599, United States

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