Steroid showdown: which drug saves more lives in severe pneumonia?

NCT ID NCT06892197

First seen Mar 29, 2026 · Last updated May 16, 2026 · Updated 7 times

Summary

This study compares two common steroids—hydrocortisone and prednisolone—in adults hospitalized with severe community-acquired pneumonia. The main goal is to see if one reduces deaths within 30 days more than the other. About 1,600 participants will be randomly assigned to receive one of the two drugs, and researchers will track survival, side effects, and need for intensive care.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amager Hospital

    RECRUITING

    Copenhagen, Copenhagen City, 2300, Denmark

  • Bispebjerg Hospital

    RECRUITING

    Copenhagen, Copenhagen City, 2400, Denmark

  • Bornholm Hospital

    RECRUITING

    Rønne, Bornholm, 3700, Denmark

  • Frederiksberg Hospital

    RECRUITING

    Frederiksberg, Copenhagen City, 2000, Denmark

  • Gentofte Hospital

    RECRUITING

    Hellerup, Copenhagen City, 2900, Denmark

  • Herlev Hospital

    RECRUITING

    Herlev, Copnhagen Surroundings, 2730, Denmark

  • Holbæk Sygehus

    RECRUITING

    Holbæk, Region Sjælland, 4300, Denmark

  • Hvidovre Hospital

    RECRUITING

    Hvidovre, Copnhagen Surroundings, 2650, Denmark

  • Nordsjællands Hospital

    RECRUITING

    Hillerød, North Zealand, 3400, Denmark

  • Næstved Sygehus

    RECRUITING

    Næstved, Region Sjælland, 4700, Denmark

  • Ringsted Sygehus

    RECRUITING

    Ringsted, Region Sjælland, 4100, Denmark

  • Slagelse Sygehus

    RECRUITING

    Slagelse, Region Sjælland, 4200, Denmark

  • University Hospital of Region Zealand, Køge

    RECRUITING

    Køge, Region Sjælland, 4600, Denmark

  • University Hospital of Region Zealand, Roskilde

    RECRUITING

    Roskilde, Region Sjælland, 4000, Denmark

Conditions

Explore the condition pages connected to this study.